These Simple Laws Explain How the World Works

One of life’s small hassles is getting ketchup out of the bottle. What does physics tell us about it—and why doesn’t banging the bottom of the bottle help?

It’s a great disappointment to me that ketchup bottles are now made out of plastic rather than glass because now you can squeeze them and you don’t get to appreciate this nice bit of physics. We’ve all been in a pub or a diner, where you have a glass bottle of ketchup. You turn it upside-down, shake it, hit the bottom, and the ketchup doesn’t come out. Then it all comes out at once! [Laughs]

That’s not random. It happens because ketchup has got this weird property known as shear thinning. What that means is, it’s really viscous until you force it to move a little bit. When you’re shaking the bottle, the ketchup can’t go anywhere, so it stays thick. Once you hit it hard enough that it has to go somewhere, then it becomes runny, so a whole load of ketchup comes out at once.

Source: These Simple Laws Explain How the World Works

HgA1C and the Prediction of DM2

RESULTS – During long-term follow-up of children and adolescents who did not initially have diabetes, the incidence rate of subsequent diabetes was fourfold (in boys) as high and more than sevenfold (in girls) as high in those with HbA1c ≥5.7% as in those with HbA1c ≤5.3%—greater rate ratios than experienced by adults in the same HbA1c categories. Analyses of ROCs revealed no significant differences between HbA1c, FPG, and 2hPG in sensitivity and specificity for identifying children and adolescents who later developed diabetes. CONCLUSIONS – HbA1c is a useful predictor of diabetes risk in children and can be used to identify prediabetes in children with other type 2 diabetes risk factors with the same predictive value as FPG and 2hPG.

Source: Diabetes Care

The 6-Minute-Walk Distance Test as a Chronic Obstructive Pulmonary Disease Stratification Tool. Insights from the COPD Biomarker Qualification Consortium: American Journal of Respiratory and Critical Care Medicine: Vol 194, No 12

Source: The 6-Minute-Walk Distance Test as a Chronic Obstructive Pulmonary Disease Stratification Tool. Insights from the COPD Biomarker Qualification Consortium: American Journal of Respiratory and Critical Care Medicine: Vol 194, No 12