Micro-clots and long COVID (it’s a hypothesis people)

But many hematologists and COVID-19 researchers worry that enthusiasm for the clot hypothesis has outpaced the data. They want to see larger studies and stronger causal evidence. And they are concerned about people seeking out unproven, potentially risky treatments.

Nature 608, 662-664 (2022)
doi: https://doi.org/10.1038/d41586-022-02286-7

This is a good article on the micro-clot hypothesis behind long Covid.

Don’t bother with the herpes article but if you have to, here you go:

doi: https://doi.org/10.1038/d41586-022-02296-5

The Biggest Life Event That No One Talks About

Retirement is more than a transition in our relationship with money. It is a major shift in our sense of self. The work that has defined our lives for decades begins to fade from view. Everything about life is different after retirement, down to the minute details of the daily routine. I think it is important to ask yourself, who am I without my job, without my career? And more importantly, how will I spend my time? How will I spend my days, weeks, months, seasons, and years once the routine ends? These are vital questions for anyone contemplating retirement. For many, the allure of endless days on the beach or in the garden loses its luster quite fast. The risk of becoming bored is a real and unexpected risk that many retirees face.

https://blairbellecurve.com/the-biggest-life-event-that-no-one-talks-about/

The endless string of triple digit days has finally ended. I’m so thankful that it’s not Too Hot to Blog and the writing is free and effortless once again. I’m still thinking strategy because having A Plan is Not a Strategy – Update 08.03.22. Yet time and time again the question begs an answer. How will I spend my time in retirement?

As long as I continue working the question doesn’t require an answer.

I guess I’ll keep working.

What do we know about Covid-19 vaccines in under 5s?

How researchers and public health officials perceive the risk-benefit ratio of rolling out vaccines to under 5s varies around the world and depends on the impact covid-19 has had on that country. Sweden has had just a handful of fatalities in those aged under 18,6 and vaccines are still not available to children aged 5-11 years. But in Brazil the virus has killed an average of two children under the age of 5 each day7—a rate which equates to around one in every five deaths among under 5s worldwide. Understandably, doctors are keen to boost protection levels, fearful of the impact that future variants might have.

BMJ 2022;378:o1892 — https://doi.org/10.1136/bmj.o1892 (Published 23 August 2022)

Marijuana and hallucinogen use among young adults reached all-time high in 2021

Alcohol remains the most used substance among adults in the study, though past-year, past-month, and daily drinking have been decreasing over the past decade. Binge drinking (five or more drinks in a row in the past two weeks) rebounded in 2021 from a historic low in 2020, during the early stages of COVID-19 pandemic. On the other hand, high-intensity drinking (having 10 or more drinks in a row in the past two weeks) has been steadily increasing over the past decade and in 2021 reached its highest level ever recorded since first measured in 2005.

Marijuana and hallucinogen use among young adults reached all-time high in 2021 — https://www.nih.gov/news-events/news-releases/marijuana-hallucinogen-use-among-young-adults-reached-all-time-high-2021

Yikes!

Green is Not Green

According to a report by Friends of the Earth (FoE), lithium extraction inevitably harms the soil and causes air contamination. As demand rises, the mining impacts are “increasingly affecting communities where this harmful extraction takes place, jeopardising their access to water,” says the report.


In pictures: South America’s ‘lithium fields’ reveal the dark side of our electric future — https://www.euronews.com/green/2022/02/01/south-america-s-lithium-fields-reveal-the-dark-side-of-our-electric-future

Great pictures. Scary story.

Scarier than Going Green is Not Cheap – Updated 07.04.22

Monoclonal Antibody RX and Covid Variants

Most monoclonal antibody therapies that neutralized early variants of the SARS-CoV-2 virus are less effective or not effective against the BA.2.12.1, BA.4, and BA.5 Omicron subvariants that currently make up almost 99% of infections in the United States, according to a report in Nature.

Evolving Omicron Subvariants Are More Resistant to Antibody Therapy — https://jamanetwork.com/journals/jama/fullarticle/2795047

Oops.

Covid’s Persistent Pattern

The government is planning on rolling out updated Omicron-targeting booster shots this fall, specifically with a component of the BA.5 subvariant, which now accounts for 85% of U.S. infections. Even if some other Omicron sublineage becomes dominant by then, the shots could be a better match against what’s circulating than the original formulation — and could help bolster protection against infection, and in turn act as a drag on transmission. The updated shot will combine the BA.5 component with the original vaccines that targeted the virus’s spike protein from early 2020. Training the immune system on two variants can lead to a broader response generally, said Meagan Deming, a virologist and infectious diseases physician at the University of Maryland. 

Covid has settled into a persistent pattern — and remains damaging. — https://www.statnews.com/2022/08/04/covid-has-settled-into-a-persistent-pattern-and-remains-damaging-it-may-not-change-anytime-soon/

Got Kids? READ THIS

Beyond just online platforms, the new survey finds that the vast majority of teens have access to digital devices, such as smartphones (95%), desktop or laptop computers (90%) and gaming consoles (80%). And the study shows there has been an uptick in daily teen internet users, from 92% in 2014-15 to 97% today. In addition, the share of teens who say they are online almost constantly has roughly doubled since 2014-15 (46% now and 24% then).These are some of the findings from an online survey of 1,316 teens conducted by the Pew Research Center from April 14 to May 4, 2022

Teens, Social Media and Technology 2022 — https://www.pewresearch.org/internet/2022/08/10/teens-social-media-and-technology-2022/

Remember my earlier post I Thought I Told You To Put That Phone Down! This earlier post has additional links to other posts on the topic of social media addiction.

Technology addictions, also commonly known as digital addictions or internet addictions, are often overlooked due to the acceptance that society has placed on using digital devices. Technology addictions often go unnoticed by loved ones because the addicted individual may appear as though they are tending to something important such as work-related tasks on their digital device, when in reality hiding behind the screen is something extraneous. When a technological problem does develop and is noticed it is often not viewed as being an imminent risk akin to an addiction to alcohol or drugs because not only is it more acceptable, but it is also not viewed as being acute or deadly. Despite these beliefs, pathological technology use can indeed be pervasive and detrimental to one’s health and well being. In a growing digital age there is a rapid expansion of digital use and subsequent potential for problematic pathological technology use to ensue.

https://www.familyaddictionspecialist.com/blog/the-6-most-common-types-of-technology-addiction

The link provided above is neither an endorsement or evidence of a previous or existing patient-therapist relationship.

Although I will admit to a quasi-addiction to You Tube for new music.