High-protein diets boost artery-clogging plaque

High-protein diets boost artery-clogging plaque, mouse study shows

In mice.

The mice on the high-fat, high-protein diet developed worse atherosclerosis — about 30% more plaque in the arteries — than mice on the high-fat, normal-protein diet, despite the fact that the mice eating more protein did not gain weight, unlike the mice on the high-fat, normal-protein diet.

“This study is not the first to show a telltale increase in plaque with high-protein diets, but it offers a deeper understanding of the impact of high protein with the detailed analysis of the plaques,” Razani said. “In other words, our study shows how and why dietary protein leads to the development of unstable plaques.”

Actos Slows IMT

Medical News: ADA: Carotid Intima-Media Thickening Slowed with Pioglitazone – in Meeting Coverage, ADA from MedPage Today

Thiazolidinediones such as pioglitazone have been shown to prevent or delay the onset of diabetes when given to patients at high risk of developing diabetes. But other studies have found that the drug class appears to inhibit the development of atherosclerosis.