Bupropion

Snorting bupropion – The Poison Review

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Snorting bupropion | The Poison Review.

The abuse of bupropion by pulverizing and snorting the medication has been described at least as far back as 2002. Bupropion inhibits re-uptake of dopamine and norepinephrine, but apparently has little or no effect on serotonin. It is abused for its psychotropic effects that resemble those of amphetamine and cocaine..

A hallmark of overdose with sustained-release or extended-release bupropion formulations is delayed onset of seizures — sometimes more than 8 hours after ingestion. When these preparations are crushed and insufflated, absorption is rapid and manifestations would be expected to come on more quickly.

– See more at: http://www.thepoisonreview.com/2014/11/12/snorting-bupropion/#sthash.35NLtujG.dpuf

FDA Approves Bupropion/Naltrexone Contrave for Obesity

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FDA Approves Bupropion/Naltrexone Contrave for Obesity.

If I’m understanding this correctly we now have an anti-depressant combined with a drug originally approved for treating opioid, then alcohol addiction, approved by the FDA to treat obesity.

This will be interesting.

UPDATE

Obesity drugs have side effects. The reason it’s taken three years for the FDA to approve NB32/Contrave is that obesity drugs have serious side effects. So serious, in fact, that several major diet drugs have been yanked from the market, making doctors, regulators and yes, investors shy away. Cardiovascular disease and mood problems are just two of the potentially serious side effects associated with Qsymia and Belviq. Older drugs Xenical  and Alli carry a risk of permanent liver and kidney damage.  And those weight loss supplements you buy over the counter? Some are deadly.

via Contrave: Is This The Weight Loss Drug We’ve Been Waiting For?.

Like I said, this will be interesting.