FDA Warns Chantix May Up Heart Risk

A meta-analysis ordered by the agency and conducted by drugmaker Pfizer found a higher occurrence of major adverse cardiovascular events — including death, MI, and stroke — with the drug than with placebo.

The FDA noted, however, that such events were uncommon in both groups, and the increased risk wasn’t statistically significant.

via Chantix May Up Heart Risk, FDA Warns.

Quitting smoking is good.  Maybe quitting smoking without a pharmaceutical assist is better.  Additional link to the FDA release follows.

Safety Alerts for Human Medical Products > Chantix (Varenicline): Safety Communication – Updated Safety Review On The Risk of Cardiovascular Adverse Events.

Diet’s Role in Lowering Risk of Repeat Heart Attacks – WSJ.com

People with the healthiest diets—those with the highest intakes of fruit, vegetables, whole grains, nuts, and a higher intake of fish relative to meat poultry and eggs—were 35% less likely to die from a repeat heart attack or stroke during the length of the study, compared with those with the least healthy diets, according to the five-year study of 32,000 people in 40 countries.

They also were 28% less likely to develop congestive heart failure, 14% less likely to have an additional heart attack and 19% less likely to have a stroke.

via Diet’s Role in Lowering Risk of Repeat Heart Attacks – WSJ.com.

Statin-Exercise Combo Lowers Mortality Risk

Patients who took statins and were physically fit had as much as a 70% reduction in the risk of dying during the follow-up period as compared with the least physically fit patients who were taking statins, according to Peter Kokkinos, PhD, of George Washington University in Washington, and colleagues.

Physical fitness also had an independent effect on mortality risk among patients who were not taking statins, reducing the likelihood of death during follow-up by as much as 47%, they reported online in The Lancet.

via Statin-Exercise Combo Lowers Mortality Risk.

I really need to get the gym more often.

Health Toll of Fast Food Spreads Eastward

Eating Western-style fast food on a regular basis significantly increased the risk of diabetes and coronary heart disease in a large Asian cohort, investigators reported.

The diabetes odds increased by 27% and CHD risk by 56% among Singapore residents who ate fast food at least twice a week.

The results changed little with overall dietary pattern, energy intake, or body mass index (BMI), as reported online in Circulation.

via Medical News: Health Toll of Fast Food Spreads Eastward – in Cardiovascular, Atherosclerosis from MedPage Today.

Red Yeast Rice: An Introduction NCCAM

Some red yeast rice products contain substantial amounts of monacolin K, which is chemically identical to the active ingredient in the cholesterol-lowering drug lovastatin. These products may lower blood cholesterol levels and can cause the same types of side effects and drug interactions as lovastatin.

Other red yeast rice products contain little or no monacolin K. It is not known whether these products have any effect on blood cholesterol levels.

Some red yeast rice products contain a contaminant called citrinin, which can cause kidney failure.  In a 2011 analysis of red yeast rice products sold as dietary supplements, 4 of 11 products were found to contain this contaminant.

via Red Yeast Rice: An Introduction | NCCAM.

Personally, I’m sticking with a statin.