Patients with chronic kidney disease had a significantly increased risk of death after myocardial infarction, and the risk increased as glomerular filtration rate (GFR) declined, a review of 103,000 myocardial infarction patients showed.
The excess mortality risk ranged from 17% to as much as 500% as the severity of chronic kidney disease (CKD) increased. CKD predicted heightened mortality regardless of the presence or absence of ST-segment elevation.
Watch that GFR.
Watch those QT’s.
Conclusion: Shortened and prolonged QT-interval durations, even within a reference range, are associated with increased mortality risk in the general population.
ADHD Drugs and Serious Cardiovascular Events in Children and Young Adults — NEJM
In conclusion, in our study involving children and young adults with 2.5 million person-years of follow-up, there were 3.1 serious cardiovascular events per 100,000 person-years. Although the point estimates of the relative risks for ADHD drugs did not indicate increased risk, the upper limit of the 95% confidence interval suggested that a doubling in the risk could not be ruled out. However, the absolute magnitude of any increased risk would be low.
The entire article is worth reading given the potential serious side effects of the drugs in question.
Medical News: Aspirin Holiday Is a Bad Idea – in Cardiovascular, Prevention from MedPage Today
A case-control study found that patients taking low-dose aspirin for secondary prevention who had recently discontinued the drug had a higher risk of nonfatal myocardial infarction than those who continued to take the aspirin.
Medical News: AHA: Value of Measuring CRP Questioned – in Meeting Coverage, AHA from MedPage Today
“In patients who already have a reason to be on a statin, C-reactive protein (CRP) measurement does not appear to provide any additional information about cardiovascular risk beyond traditional factors, a secondary analysis of the ASCOT trial showed.”
“Heavy cocaine users have a high prevalence of cardiac damage as seen by cardiac MRI.”
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