In a retrospective study, diabetic patients who were taking metformin had worse cognitive performance than those not taking the drug (odds ratio 2.23, 95% CI 1.05-4.75), Eileen Moore, PhD, of the University of Melbourne in Australia, and colleagues reported online in Diabetes Care.
Additionally, patients with diabetes who had vitamin B12 levels less than 250 pmol/L also had worse cognitive performance (OR 2.29, 95% CI 1.12-4.66), and the association between metformin and cognitive impairment was weakened after adjusting for vitamin B12 levels, they stated.
via In Some Patients Metformin Impairs Thinking.
Over 9 years, those who had diabetes had significantly worse cognitive decline on two separate tests compared with those who didn’t have the disease (P=0.008 and P=0.001), Kristine Yaffe, MD, of the University of California San Francisco, and colleagues reported online in the Archives of Neurology.
via Medical News: Diabetes May Speed Cognitive Decline – in Neurology, General Neurology from MedPage Today.
A study in the British Medical Journal lit up the Internet last week with the conclusion that cognitive decline begins at age 45. While it’s true that some innate skills like memory and speed of reasoning fall off as we age, other aspects of intelligence related to learning and experience actually improve.
via Patricia Cohen: The Advantages of the Middle-Age Brain | TIME Ideas | TIME.com.
Positive proof the older brain improves with time. I found an article on some positive aspects of the aging brain.
Now if I could only remember where I put my car keys…