Actos Slows IMT

Medical News: ADA: Carotid Intima-Media Thickening Slowed with Pioglitazone – in Meeting Coverage, ADA from MedPage Today

Thiazolidinediones such as pioglitazone have been shown to prevent or delay the onset of diabetes when given to patients at high risk of developing diabetes. But other studies have found that the drug class appears to inhibit the development of atherosclerosis.

Non-Glucose Metabolism Determinants in HgbA1c

Cardiovascular Disease, Neuropathy, and Retinopathy — Diabetes Care

In a study of 648 apparently healthy individuals, 12% had an elevated total A 1 level (measured in that study) not explained by measurement error or glucose intolerance and remaining in the same range over 3.5 years in 90% of those initially with high and in 68% of those initially with low baseline levels (1). There was no correlation with glucose tolerance, with caloric intake, or with physical activity, but A 1 level was associated with cigarette use and with clinically overt atherosclerosis, leading Dekker to conclude that “factors unrelated to glucose metabolism are the main determinants of A 1” in nondiabetic individuals, perhaps with bearing on risk of what are considered complications of diabetes.

Economic Burden of Diabetes Worsening

My oldest son is pre-Med.  I keep gently reminding him endocrinology is an exciting field.

Costs, Complexity of Treating Diabetes Increasing Steadily, Says Study — AAFP News Now — American Academy of Family Physicians

A recent study from the CDC and NIH shows that nearly 13 percent of adults in the United States have diabetes, but 40 percent of those individuals haven’t been diagnosed yet.