Effect of Body Mass Index on Insulin Secretion or Sensitivity and Diabetes – American Journal of Preventive Medicine

Effect of Body Mass Index on Insulin Secretion or Sensitivity and Diabetes – American Journal of Preventive Medicine.

Background

Although the association between obesity and diabetes is well known, the factors predisposing to diabetes in non-obese Asians are less clearly characterized.

Conclusions

Individuals with normal BMI may develop diabetes mainly through IIS, whereas individuals with high BMI may develop diabetes primarily through IR.

I am so screwed.

Body Mass Index and the Risk of All-Cause Mortality Among Patients with Type 2 Diabetes

Body Mass Index and the Risk of All-Cause Mortality Among Patients with Type 2 Diabetes.

Conclusions—The current study indicated a U-shaped association of BMI with all-cause mortality risk among African American and white patients with type 2 diabetes. A significantly increased risk of all-cause mortality was observed among African Americans with BMI<30 kg/m2 and BMI ≥35 kg/m2, and among whites with BMI<25 kg/m2 and BMI ≥40 kg/m2 compared with patients with BMI 30-34.9 kg/m2.

Diet Soda May Alter Our Gut Microbes And Raise The Risk Of Diabetes : The Salt : NPR

Now, a new study published in the journal Nature introduces a new idea: Diet sodas may alter our gut microbes in a way that increases the risk of metabolic diseases such as Type 2 diabetes — at least in some of us.

In the paper, researchers at the Weizmann Institute of Science in Israel describe what happened when they fed zero-calorie sweeteners, including saccharin, aspartame and sucralose, to mice.

“To our surprise, [the mice] developed glucose intolerance,” Weizmann researcher Eran Elinav tells us.

Artificial sweeteners induce glucose intolerance by altering the gut microbiota : Nature : Nature Publishing Group.

Diet Soda May Alter Our Gut Microbes And Raise The Risk Of Diabetes : The Salt : NPR.

Diabetes and the Heart: Risk Greater in Women

Diabetes and the Heart: Risk Greater in Women.

Data from 64 studies with both male and female participants yielded a 44% greater multiple-adjusted relative risk ratio (RRR) for incident coronary heart disease (CHD) in women compared with men (RRR 1.44, 95% CI 1.27-1.63), Rachel Huxley, DPhil, of the University of Queensland in Sydney, Australia, and colleagues found.

Pooled data from 52 studies indicated that women also had a 44% greater chance than men of dying from fatal CHD associated with diabetes, Huxley and colleagues reported online in the journal Diabetologia.

Dietary Determinants of Hepatic Steatosis and Visceral Adiposity in Overweight and Obese Youth at Risk of type 2 Diabetes

Conclusion: Hepatic steatosis is associated with a greater intake of fat and fried foods, whereas visceral obesity is associated with increased consumption of sugar and reduced consumption of fiber in overweight and obese adolescents at risk of type 2 diabetes. This study was registered at clinicaltrials.gov as NCT00755547.

via Dietary determinants of hepatic steatosis and visceral adiposity in overweight and obese youth at risk of type 2 diabetes.