FDA Okays Naloxegol Movantik in Opioid-Induced Constipation

If you read the source article you’ll never look at constipation the same way ever again. Better dig deeper to find out why your applicant is constipated.  It may not be just a horrible diet and lack of dietary fiber.

And yet another FDA approved drug to counteract adverse effects from another FDA approved drug.

FDA Okays Naloxegol Movantik in Opioid-Induced Constipation.

The US Food and Drug Administration (FDA) has approved naloxegol (Movantik, AstraZeneca Pharmaceuticals), a peripherally acting opioid receptor antagonist, for the treatment of opioid-induced constipation (OIC) in adults with chronic noncancer pain.

OIC is a common adverse effect of opioid use. An estimated 40% to 80% of patients receiving long-term opioid therapy experience OIC, which can be severe enough to cause discontinuation of opioid therapy.

Most Emergency Room Super Frequent Users Have Addiction Disorder – MedicalResearch.com

Most Emergency Room Super Frequent Users Have Addiction Disorder | Medical Research News and Interviews: MedicalResearch.comMedical Research News and Interviews: MedicalResearch.com.

MedicalResearch: What are the main findings of the study?

 

Answer: We found that within our group of 255 known Emergency Department “super-frequent users,” 77% had with some type of addiction disorder, and 47 percent visited the Emergency Department seeking narcotics for pain. Women were more likely to be narcotic seeking. Using our individualized Electronic Medical Record care plan intervention, created and overseen by our multidisciplinary team (comprised of Emergency Department staff physicians, a psychologist, residents, nurses and support staff), we found that our plan significantly decreased annual rates of visits by these super-frequent users and those who sought pain-relief narcotics and other super-frequent users.

Vital Signs: Overdoses of Prescription Opioid Pain Relievers and Other Drugs Among Women — United States, 1999–2010

Between 1999 and 2010, OPR overdose deaths increased more than fivefold among women (a total of 47,935 OPR overdose deaths during that period).

via Vital Signs: Overdoses of Prescription Opioid Pain Relievers and Other Drugs Among Women — United States, 1999–2010.

This story was covered by all of the mainstream media outlets.  Read the source article from MMWR to grasp the significance of this health issue.  Scary stuff.

The War to Our South – Mexico Dissolves Their FBI And Moves To Legalize Drugs

President-elect Enrique Pena and his Institutional Revolutionary Party (PRI) who won control of Mexico’s government on July 1st, moved to dissolve the Agencia Federal de Investigación (AFI). Modeled after the United States FBI, the AFI was founded in 2001 to crack down on Mexico’s pervasive government corruption and drug trafficking. With rival drug cartels murdering between 47,500 to 67,000 Mexicans over the last six years, the move by the PRI represents the total surrender of Mexico’s sovereignty back to the money and violence of Mexico’s two main drug cartels, the Sinaloa Federation and Los Zetas. Coupled with the Obama Administration’s “Dreamer” Executive Order curtailing deportations of illegal aliens, a hands-off policy on both sides of the border foreshadows a huge increase in “narco-trafficking” violence and corruption flooding into the United States.

via Testosterone Pit – Home – Mexico Dissolves Their FBI And Moves To Legalize Drugs.

The War to Our South – 8/27/11

BBC News – Mexico drugs crisis: Monterrey shocked by casino attack

The attack was a bold move by the gangs. It happened in broad daylight, was aimed at civilians and took place in the heart of the city.

BTW, the last travel warning for Mexico from the US State Department is dated 4/22/11 or approximately 5,000 corpses ago.  One of the world’s largest life reinsurance company’s manual still maintains a Standard rating for Mexico.

Well, OK then.