Source: Researchers Identify Genetic Links to Cannabis Dependence
life underwriting
Small GISTs More Deadly Than Previously Thought
Concurrent Cocaine, Alcohol Use Linked to Suicidality
Cholesterol Lowering in Intermediate-Risk Persons without Cardiovascular Disease — NEJM
Conclusions: Treatment with rosuvastatin at a dose of 10 mg per day resulted in a significantly lower risk of cardiovascular events than placebo in an intermediate-risk, ethnically diverse population without cardiovascular disease. (Funded by the Canadian Institutes of Health Research and AstraZeneca; HOPE-3 ClinicalTrials.gov number, NCT00468923.)
Source: Cholesterol Lowering in Intermediate-Risk Persons without Cardiovascular Disease — NEJM
Source: Blood-Pressure Lowering in Intermediate-Risk Persons without Cardiovascular Disease — NEJM
Source: Blood-Pressure and Cholesterol Lowering in Persons without Cardiovascular Disease — NEJM
JAMA Cardiology – Effect of the Presence and Type of Angina on Cardiovascular Events in Patients Without Known Coronary Artery Disease Referred for Elective Coronary Angiography
This study describes the characteristics of patients referred for typical, atypical, or no angina and examines the associations between angina type, pre–cardiac catheterization stress test results, and burden of coronary atherosclerosis identified on coronary angiography.
In this short research letter we find further lack of utility for stress tests in the manner for which we are currently using them for risk stratification. The authors categorized patients referred for catheterization without known CAD to groups based on chest pain symptoms of: typical, atypical, or absent. They then looked at their stress test results, categorized as positive or negative, and found that a negative stress test did not help predict those without obstructive CAD on catheterization. Specifically, patients with typical angina symptoms and a negative stress test were the MOST likely to have obstructive CAD (74%). Clearly limited by the nature of the data presented, and the limited information given regarding the methodology in this research letter, it does further raise doubts regarding the utility of stress testing to risk stratify patients for CAD.
HT to Jeremy Fried for the observation quoted above. Source: Research and Reviews R&R in the FastLane | LITFL: Life in the Fast Lane Medical Blog
Pets Are Good For Humans’ Health – NPR
Eric O’Grey was 51, obese and suffering from diabetes and high cholesterol when he took home an overweight shelter dog. Now the duo are headlining a campaign on how pets improve humans’ lives.
Source: Eric And Peety Make The Case That Pets Are Good For Humans’ Health : Shots – Health News : NPR
The video located in the website link above is a must see. Wonderful story!
CNS – Pfizer to Face Testosterone Claims
Source: CNS – Pfizer to Face Testosterone Claims After All
The multi-district master complaint asserted 10 primary state law claims, including strict liability based on design defect and failure to warn, negligence, breach of implied and express warranty, fraud, consumer protection, and unjust enrichment.
The plaintiffs also allege non-tort claims for wrongful death, survival, loss of consortium, and punitive damages.
One of the books I’m reading is Powerful Medicines – The Benefits, Risks, and Costs of Prescription Drugs written by Jerry Avorn M.D. Definitely a fun read in the context of our culture’s addiction to the quick fix. Whatever ails you there is a pill that promises to fix everything. Dr. Avorn’s book is packed with information. Simply stated, there are benefits and risks associated with any medication. Ultimately it is the consumer’s responsibility to know and understand what those benefits and risks are with anything you put in your body.
It was clear to me from the beginning that the unsuspecting and too trustful public was going to be introduced to a new disease Low-T. The pharmaceutical strategy was just another medicalization of a natural process.
More. Drugs. Please.
Drugs That May Induce Raynaud’s – Medpage Today
Incidence of side effect is probably underestimated
Source: RheumNow: Drugs That May Induce Raynaud’s | Medpage Today
Pot Smokers May Face 5 Times Greater Risk of Alcohol Abuse
Marijuana users also less likely to quit drinking, researchers say
Source: Pot Smokers May Face 5 Times Greater Risk of Alcohol Abuse
How to roll a joint video: 10 easy steps to roll the perfect joint
One of legal cannabis’ tremendously modern luxuries is the pre-roll joint. No longer do you have to buy sub-par product from your dealer, work the seeds-and-stems quality control, grind it up and roll your own joint. Now you can walk into a store and purchase a pre-roll — or a package of pre-rolls. You can mix-and-match different strain pre-rolls. Some shops let you choose between the regular and mini-joints. And some will even offer an option wrapped in 24K gold rolling papers.
Source: How to roll a joint video: 10 easy steps to roll the perfect joint
Times have changed, no?
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