liver failure

Scary Charts – 07.16.23

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Note the Pandemic Bump. Overall trend lines for both CA and USA still heading north.

CA only. USA death rates probably show a similar pattern.

CA statistics. NOTE the ASIAN RATE.

Excessive drinking during the covid-19 pandemic increased alcoholic liver disease deaths so much that the condition killed more Californians than car accidents or breast cancer, a KFF Health News analysis has found. Lockdowns made people feel isolated, depressed, and anxious, leading some to increase their alcohol intake. Alcohol sales rose during the pandemic, with especially large jumps in the consumption of spirits.

Excessive Drinking During the Pandemic Increased Alcoholic Liver Disease Death Rates — https://kffhealthnews.org/news/article/excessive-drinking-during-the-pandemic-increased-alcoholic-liver-disease-death-rates/

Yes it’s Sunday morning and I’m thinking about single malt Scotch because I ran out.

Take Home Lesson for UW Professionals

The highest mortality rates were Gen X and Boomers.

Memo to Self

Think before you drink.

Mass Destruction

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ISSUE: The FDA is advising consumers to immediately stop using a product called Mass Destruction, marketed as a dietary supplement for muscle growth. The product is labeled to contain at least one synthetic anabolic steroid and has been linked to at least one reported serious illness.

BACKGROUND: The FDA was alerted by the North Carolina Department of Health and Human Services of a serious injury associated with use of Mass Destruction. The report described a previously healthy 28-year-old male with liver failure requiring transplant after several weeks of product use. Mass Destruction is manufactured for Blunt Force Nutrition in Sims, N.C. and sold in retail stores, fitness gyms, and on the Internet. An investigation is underway to identify the product’s manufacturer.

via Safety Alerts for Human Medical Products > Muscle Growth Product Called Mass Destruction: FDA Health Risk Warning – Undeclared Ingredients.

Finally a product that lives up to its name.

Acute Hepatitis and Liver Failure Following the Use of a Dietary Supplement Intended for Weight Loss or Muscle Building — May–October 2013

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On September 9, 2013, the Hawaii Department of Health (HDOH) was notified of seven patients with severe acute hepatitis and fulminant liver failure of unknown etiology. Patients were previously healthy and sought medical care during May-September 2013. Clinicians reported that the seven patients had all used OxyELITE Pro, a dietary supplement marketed for weight loss and muscle gain, before illness onset.

via Notes from the Field: Acute Hepatitis and Liver Failure Following the Use of a Dietary Supplement Intended for Weight Loss or Muscle Building — May–October 2013.

Oops.

Arava (leflunomide) – Watch Those Liver Enzymes

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Medical News: FDA Adds Liver Failure Warning to RA Drug – in Product Alert, Prescriptions from MedPage Today

The FDA has expanded the black box warning to the label of the rheumatoid arthritis drug leflunomide (Arava) to include possible fatal liver damage.

The agency received 49 adverse event reports — including instances of jaundice, coagulopathy, encephalopathy, and 14 fatalities — about the drug from August 2002 to May 2009. Of the patients reporting adverse events, 36 were hospitalized.