liver injury

Deaths from Cirrhosis rose in all but one state between 1999-2016

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Liver disease deaths jumped by 65 percent in the United States, from 1999-2016, disproportionately affecting adults ages 25-34. The increase in deaths among young adults was driven entirely by alcohol-related liver disease, according to a new study.

Liver specialist Elliot B. Tapper, M.D., says he’s witnessed the disturbing shift in demographics among the patients with liver failure he treats at Michigan Medicine. National data collected by Tapper and study co-author Neehar Parikh, M.D., M.S., confirms that in communities across the country more young people are drinking themselves to death.

Read the source article here.

 

 

Increases in Liver Injury Related to Herbal and Dietary Supplements — Physician’s First Watch

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Researchers analyzed registry data from some 800 patients with liver injury either from medications excluding acetaminophen or herbal and dietary supplements. In the first 2 years of the registry, 7% of cases were due to herbal and dietary supplements, a proportion that increased to 20% a decade later. Hepatotoxicity from non-bodybuilding-related supplements required liver transplantation more often than injury from conventional drugs 13% vs. 3%; there were no cases of liver transplantation associated with bodybuilding supplements.

via Increases in Liver Injury Related to Herbal and Dietary Supplements — Physician’s First Watch.

Acetaminophen Prescription Combination Drug Products with more than 325 mg: FDA Statement – Recommendation to Discontinue Prescribing and Dispensing

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ISSUE: FDA is recommending health care professionals discontinue prescribing and dispensing prescription combination drug products that contain more than 325 milligrams (mg) of acetaminophen per tablet, capsule or other dosage unit. There are no available data to show that taking more than 325 mg of acetaminophen per dosage unit provides additional benefit that outweighs the added risks for liver injury. Further, limiting the amount of acetaminophen per dosage unit will reduce the risk of severe liver injury from inadvertent acetaminophen overdose, which can lead to liver failure, liver transplant, and death.

via Safety Alerts for Human Medical Products > Acetaminophen Prescription Combination Drug Products with more than 325 mg: FDA Statement – Recommendation to Discontinue Prescribing and Dispensing.

You like your liver?  You can keep your liver.