In a registry-based cohort study, Seena Fazel and colleagues test for within-individual associations between SSRI prescription and violent crime.
Source: PLOS Medicine: Selective Serotonin Reuptake Inhibitors and Violent Crime: A Cohort Study
In a registry-based cohort study, Seena Fazel and colleagues test for within-individual associations between SSRI prescription and violent crime.
Source: PLOS Medicine: Selective Serotonin Reuptake Inhibitors and Violent Crime: A Cohort Study
There are multiple links in the WP article to the original studies.
FDA Stiffens Warning on NSAID Cardiovascular Risk | Medpage Today.
Thought I would add a link to the actual FDA alert.
NSAIDs can increase the risk of heart attack or stroke in patients with or without heart disease or risk factors for heart disease. A large number of studies support this finding, with varying estimates of how much the risk is increased, depending on the drugs and the doses studied.
There’s also the issue of cost. The medicines are expected to come with a price tag of $7,000 to $12,000 per patient per year, according to the Wall Street Journal’s Pharmalot blog, costing the US health system as much as $23 billion a year. “These injectable drugs are already viewed by payers as potential budget busters along the lines of treatments for hepatitis C and some cancers,” Ed Silverman wrote.
via There’s still a lot we don’t know about the new cholesterol-lowering drugs – Vox.
According to some reports metformin poisoning, though rare, is associated with a mortality rate of 30%.
via Hemodialysis in metformin poisoning | The Poison Review.
Yikes.
“When we see something that surprises us and flies in the face of what is understood, it requires another look — maybe a different cohort, larger numbers, longer follow-up,”
via Intensive Tx Fails to Slow Atherosclerosis | Medpage Today.
Surprised? As long as we continue to focus on pharmaceuticals as the answer, no one should be surprised.
More on the aspirin debate.
Should patients stop taking aspirin for primary prevention? : Cleveland Clinic Journal of Medicine.
A 2013 report by the federal Substance Abuse and Mental Health Services Administration found that emergency room visits related to nonmedical use of prescription stimulants among adults 18 to 34 tripled from 2005 to 2011, to almost 23,000.
via Workers Seeking Productivity in a Pill Are Abusing A.D.H.D. Drugs – NYTimes.com.
“It is necessary — necessary for survival of the best and the smartest and highest-achieving people.”
Comparison of opioid analgesic-related mortality between those enrolled or not enrolled in Medicaid shows considerably higher death rates and a more rapid increase in mortality among Medicaid enrollees. The consistently higher age-adjusted death rates for poisonings involving opioid analgesics among Medicaid enrollees (after stratifying data by sex) suggest that differences in age and sex distributions do not underlie these Medicaid/non-Medicaid differences. Other factors, such as the greater prevalence of mental illness and substance abuse in the Medicaid population (6), might contribute to the observed differences.
via Poisoning Deaths Involving Opioid Analgesics — New York State, 2003–2012.
Maybe the title should be Socioeconomic Status and Death.
5 Takeaways from the Diabetes Drugs Investigation | Medpage Today.
At least 3,300 deaths and 20,000 hospitalizations have been linked to new diabetes drugs in adverse event reports submitted by clinicians and pharmaceutical companies to the FDA since 2004.
Read and pay close attention to the chart of adverse events by drug. The lizard strikes back (Byetta).
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