Causality was called very likely due to flavocoxid in three patients and possibly due to the agent in one patient, as that case was complicated by exposure to several other agents that may have caused the injury, including pregabalin (Lyrica), duloxetine (Cymbalta), and tizanidine (Zanaflex).
pharmaceutical
Teva’s Adderall 30 mg Tabs – Counterfeit Product – Contains Wrong Active Ingredients
The counterfeit Adderall tablets are round, white and do not have any type of markings, such as letters or numbers. Authentic Adderall 30 mg tablets produced by Teva are round, orange/peach, and scored tablets with “dp” embossed on one side and “30” on the other side of the tablet.
Adderall contains four active ingredients – dextroamphetamine saccharate, amphetamine aspartate, dextroamphetamine sulfate, and amphetamine sulfate. Instead of these active ingredients, the counterfeit product contained tramadol and acetaminophen, which are ingredients in medicines used to treat acute pain.
If you or your child is bouncing off the walls AND you bought Adderall off the Internet, check to see if your tablets are white and have no markings.
DailyMed – Current Medication Information
Here is another medication information resource I like a lot. It is from the NLM and NIH. I’m also adding a link on the sidebar.
The Conundrum Between Maturity and ADHD
A recent Canadian study showed that the youngest children in each grade (born in the earliest month of the Canadian grade cutoff: December) were 30% more likely to be diagnosed with ADHD than the oldest children (born in January). For girls, who overall have a lower incidence of ADHD, the difference was even more pronounced: 70%.
Interestingly, the overall rate of ADHD diagnosis in the sampling of children from this Canadian study (900,000 children) was 6.9% for boys and 2.2% for girls. Rates of diagnosis here in the United States are much higher, creeping up on 10% of all children.
via The conundrum between maturity and ADHD.
Medications are not without their side effects…
Minor Trauma Led to Death in Pradaxa Patient
Dabigatran etexilate is an oral anticoagulant that acts as a direct, competitive thrombin inhibitor. It does not require routine monitoring and has been approved by the FDA for the prevention of stroke and systemic embolism in patients with atrial fibrillation. Note, however, that no effective reversal agent for dabigatran in the event of catastrophic hemorrhage has been identified.
On the article’s webpage you’ll find a link to download a PDF copy of the source article.
FDA Adds Diabetes Warning to Statin Labels
The diabetes warning has been rumored as a possibility since the findings from the JUPITER trial of rosuvastatin revealed an unexpected 27% increase in new onset diabetes among patients randomized to the statin.That finding was especially perplexing because JUPITER was a study of statins in patients who had no history of cardiovascular disease, the so-called healthy patient trial. Moreover, based on the JUPITER results, the FDA approved rosuvastatin for primary prevention.The FDA said hyperglycemia was also observed among patients treated with 40-mg atorvastatin in a substudy of PROVE-IT TIMI 22, and a meta-analysis of data from 13 statin trials “reported that statin therapy was associated with a 9% increased risk for incident diabetes.”
Effect of Aspirin on Vascular and Nonvascular Outcomes Meta-analysis
Conclusion: Despite important reductions in nonfatal MI, aspirin prophylaxis in people without prior CVD does not lead to reductions in either cardiovascular death or cancer mortality. Because the benefits are further offset by clinically important bleeding events, routine use of aspirin for primary prevention is not warranted and treatment decisions need to be considered on a case-by-case basis.
Antidepressant Use Soaring – MayoClinic.com
One in 10 people over age 12 in the United States is taking an antidepressant, according to the National Health and Nutrition Examination Survey, which is conducted by the Center for Disease Control. Women between the ages of 40 and 59 are the most likely group to take antidepressants. In this age range, 23 percent of U.S. women are taking one.
via Antidepressant use soaring among Americans 12 and over – MayoClinic.com.
Effect of Two Intensive Statin Regimens on Progression of Coronary Disease — NEJM
Acetaminophen OD More Deadly if Taken in Stages
Those who ingested more than 4,000 mg of acetaminophen in a single day spread out over more than one time point had a significantly higher mortality rate compared with those who overdosed at a single time point (37.3% versus 27.8%, P=0.025), according to Kenneth Simpson, MD, of the University of Edinburgh in Scotland, and colleagues.
The cohort analysis included 663 patients admitted with acetaminophen-induced severe liver injury from November 1992 through October 2008. About one-quarter (24.3%) overdosed in a staggered fashion, defined as taking at least two excessive doses separated by more than eight hours and adding up to more than 4,000 milligrams in one day. The rest of the patients ingested that much at a single time point.
Most of the patients who had a staggered overdose (58.2%) said that pain relief was the reason they repeatedly took an excessive dose. Another 34.3% said it was a suicide attempt.
Learn more at Acetaminophen Toxicity.
Personally I rarely take the stuff. It’s pure poison for the liver.
lifeunderwriter.net 
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