
pharmaceutical
Question of the Day – Do You Pay Attention to Non-Adherence?
Effect of Statin Adherence on Cerebrovascular Disease in Primary Prevention
Non-adherence to statins was prevalent with just 55% of patients exposed to ≥80% of the medications during follow-up.

Saxagliptin (Onglyza) – Think DM2
Onglyza? Somebody got paid to name this drug. Think about that for a while.

Alimta – Think Strong Stuff for a Bad Disease
Alimta Approved as Maintenance Therapy for Advanced Lung Cancer – US News and World Report
The drug Alimta (pemetrexed) has been approved by the U.S. Food and Drug Administration to prevent progression of certain types of advanced or metastatic (spreading) lung cancer, the agency said Monday.
Dronedarone Multaq (think AFib)
Where do these guys come up with these names???
Varenicline and Suicide Risk
Throughout the marketing history of the drugs, there have been 98 suicides and 188 attempted suicides in varenicline users and 14 suicides and 17 attempted suicides in bupropion users, the agency (FDA) reported.
Stay Calm – Do Not Stop Taking Your Insulin
Published online in Diabetologia, three of the four studies found some type of cancer-related association with the long-acting insulin analog.
I have a link to Diabetologia on my sidebar if you are interested in downloading the original studies.
New Byetta Studies
FDA Warning of Byetta Pancreatitis Side Effects Contradicted by New Studies – AboutLawsuits.com
Note where this original post is located. Let’s all wait and see if the FDA changes their position on the drug.
Rosiglitazone Doubles Risk of Heart Failure
Take Home Lesson:
Consider simply adding the usual recommended debits for CHF to the DM rate.
After all, the HF risk is doubled but not the mortality. And critics of this study question its statistical validity.
Actos Slows IMT
Thiazolidinediones such as pioglitazone have been shown to prevent or delay the onset of diabetes when given to patients at high risk of developing diabetes. But other studies have found that the drug class appears to inhibit the development of atherosclerosis.
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