SCD

Apnea: ‘Sleeping Gun’ in Sudden Death?

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After adjustment for other risk factors, each 10% decrease in the lowest nocturnal oxygen saturation among adults undergoing a first-time polysomnogram for suspected sleep-disordered breathing was associated with a 14% greater risk of sudden cardiac death or resuscitated cardiac arrest (HR 1.14, 95% CI 1.01 to 1.27), according to Virend Somers, MD, PhD, of the Mayo Clinic in Rochester, Minn., and colleagues.

Sleep factors associated with a significantly greater likelihood of remaining free from sudden cardiac death or resuscitated cardiac arrest included an apnea-hypopnea index of less than 20 events per hour (HR 1.60, 95% CI 1.14-2.24), a mean nocturnal oxygen saturation of 93% or higher (HR 2.93, 95% CI 1.98-4.33), and a lowest nocturnal oxygen saturation of 78% or higher (HR 1.81, 95% CI 1.28-2.56), the researchers reported online in the Journal of the American College of Cardiology.

via Apnea: ‘Sleeping Gun’ in Sudden Death

Yes.  CPAP compliance matters.

Magnesium and Sudden Cardiac Death

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Plasma and dietary magnesium and risk of sudden cardiac death in women — Am J Clin Nutr

Conclusions: In this prospective cohort of women, higher plasma concentrations and dietary magnesium intakes were associated with lower risks of SCD. If the observed association is causal, interventions directed at increasing dietary or plasma magnesium might lower the risk of SCD.

Predictors of SCD Post MI Change With Time

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Predictors of Sudden Cardiac Death Change With Time After Myocardial Infarction: Results From the VALIANT Trial

Results: SCD occurred in 8.6% of patients during 3 years of follow-up. During the initial hospitalization for MI, the strongest predictors of SCD were atrial fibrillation (AF) (hazard ratio [HR], 2.0), prior stroke (HR, 2.0), and smoking (HR, 1.5). In the first 30 days after MI, the strongest predictors of SCD were recurrent MI (HR, 3.5), rehospitalization (HR, 2.5), and coronary artery bypass graft surgery (HR, 2.3). The strongest predictors of SCD from 30 days to 6 months after MI were prior transient ischemic attack (HR, 1.8), prior diabetes (HR, 1.7), and new left bundle branch block (HR, 1.7). From 6 months to 3 years after MI, the strongest predictors of SCD were prior MI (HR, 1.7), recurrent MI (HR, 1.7), and AF (HR, 1.6).