As seen in previous studies, patients with elevated depressive symptoms had a higher risk of MI or all-cause death through about 4 years of follow-up, after accounting for demographics, education, income, and body mass index HR 1.41, 95% CI 1.15 to 1.72, according to Siqin Ye, MD, of Columbia University in New York City, and colleagues.
underwriting
If You’re Serious About Ideas, Get Serious About Blogging
Indeed, if you want to shape public opinion, you need to be the one creating the narrative.
via If You’re Serious About Ideas, Get Serious About Blogging – Dorie Clark – Harvard Business Review.
To Revert Breast Cancer Cells, Squeeze
While the traditional view of cancer development focuses on the genetic mutations within the cell, Mina Bissell, Distinguished Scientist at the Berkeley Lab, conducted pioneering experiments that showed that a malignant cell is not doomed to become a tumor, but that its fate is dependent on its interaction with the surrounding microenvironment. Her experiments showed that manipulation of this environment, through the introduction of biochemical inhibitors, could tame mutated mammary cells into behaving normally.
Kidnappings of Foreigners on Rise in Yemen – The Observer
An Austrian man and a Finnish couple became on Friday the latest victims of abductions in the strife-torn country. Witnesses said the three were taken by masked gunmen as they made their way to a tailor’s shop in central Tahrir Square at about 4pm, during the busy afternoon shopping period.
via Kidnappings of foreigners on rise in Yemen | World news | The Observer.
Omega 3s May Be No Help Against Stroke, MI
Omega-3 polyunsaturated fatty acid supplementation does not appear to reduce the risk of cardiovascular or cerebrovascular events, a study has found.
Note that the lack of a significant effect of omega-3 supplementation is consistent with the majority of the large studies on the topic.
Hep C Drug Linked to Fatal Skin Reactions
The oral hepatitis C drug telaprevir (Incivek) will now carry a boxed warning about potentially fatal skin reactions in the wake of multiple deaths, its manufacturer said Wednesday.
via Hep C Drug Linked to Fatal Skin Reactions.
Oops.
Rock Stars: Live Fast, Die Young
It turns out that solo stars are about twice as likely to unplug early as those who play in bands, according to Mark Bellis, DSc, of Liverpool John Moores University in Liverpool UK, and colleagues.
And compared with the general population, North American stars are more likely to die than those from Europe, Bellis and colleagues reported in the online journal BMJ Open.
FDA Warns Against Combining Alcohol, Other CNS Depressants With Xyrem – AAFP News
According to the Dec. 17 statement, the FDA recently evaluated reports of patients who died while taking Xyrem — which is used to reduce instances of cataplexy and to manage other symptoms of narcolepsy — along with alcohol or other central nervous system (CNS) depressants. Although the precise cause of the deaths remains uncertain — the reports contained incomplete information and did not adequately address confounding factors, such as pre-existing sleep apnea and/or chronic obstructive pulmonary disease — given some of the circumstances noted in the deaths, the FDA determined that the recommendations in the Xyrem drug label should be strengthened to highlight the risks of using the drug in conjunction with CNS depressant drugs or alcohol.
via FDA Warns Against Combining Alcohol, Other CNS Depressants With Xyrem — AAFP News Now — AAFP.
Oops.
BBC News – Diabetes Fuels Heart Failure Risk
People with diabetes are up to 65% more likely to have heart failure, an analysis has found.
The National Diabetes Audit looked at data on almost two million people and also found increased risk of other complications, and premature death.
U-Shaped Link for BMI at DX With Mortality in DM2
U-Shaped Link for BMI at Diagnosis With Mortality in Type 2 Diabetes | insureintell.com.
CONCLUSIONS Patients categorized as normal weight or obese with T2DM within a year of diagnosis of T2DM exhibit variably higher mortality outcomes compared with the overweight group, confirming a U-shaped association of BMI with mortality. Whether weight-loss interventions reduce mortality in all T2DM patients requires study.
via The Association Between BMI Measured Within a Year After Diagnosis of Type 2 Diabetes and Mortality.
HT – Hank George
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