WTF

Tirzepatide (another GLP-1 receptor agonist post)

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Tirzepatide Reduces Appetite, Energy Intake, and Fat Mass in People With Type 2 Diabetes — https://doi.org/10.2337/dc22-1710

To reduce the number of clicks the rest of this post is a repost of April Fools 2023 (this is a GLP-1 receptor agonist post). Enjoy!

Ozempic and a similar drug, Wegovy, are weekly shots you give yourself that cause the body to produce insulin. Insulin lowers blood sugar, slows digestion and makes people feel full. Carter-Williams tried it and was amazed.

“You are not hungry,” she says. “Like, I actually have to set timers to make sure that I do eat, because otherwise you actually forget to eat.”

‘You forget to eat’: How Ozempic went from diabetes medicine to blockbuster diet drug https://www.npr.org/2023/04/01/1166781510/ozempic-weight-loss-drug-big-business

Everyone wants the easy way out. I sometimes forget to eat but not because of a miracle drug. You wonder if those of us wanting to lose weight know you can’t stop taking this drug once you start it.

Patients discontinuing the use of weight-loss drugs such as Wegovy risk regaining their original body weight in about five years, a Novo Nordisk official said on Wednesday.

Novo Nordisk Says Stopping Obesity Drug May Cause Full Weight Regain in 5 Years–https://www.medscape.com/viewarticle/990267?src=rss

Side effects?

Just a few https://www.wegovy.com/taking-wegovy/side-effects.html

  • Possible thyroid tumors, including cancer.
  • Inflammation of your pancreas (pancreatitis)
  • Gallbladder problems
  • Increased risk of low blood sugar (hypoglycemia) in patients with type 2 diabetes, especially those who also take medicines for type 2 diabetes such as sulfonylureas or insulin
  • Kidney problems (kidney failure)
  • Serious allergic reactions
  • Change in vision in people with type 2 diabetes.
  • Increased heart rate
  • Depression or thoughts of suicide.

So if you want to lose weight by taking a GLP-1 receptor agonist remember the risks of side effects including the real possibility of having to take a drug that costs up to $1600.00 a month for the rest of your life.

Good luck with that. This joke’s on you.

April Fools 2023 (this is a GLP-1 receptor agonist post)

/ SupremeCmdr / 6 Comments

Ozempic and a similar drug, Wegovy, are weekly shots you give yourself that cause the body to produce insulin. Insulin lowers blood sugar, slows digestion and makes people feel full. Carter-Williams tried it and was amazed.

“You are not hungry,” she says. “Like, I actually have to set timers to make sure that I do eat, because otherwise you actually forget to eat.”

‘You forget to eat’: How Ozempic went from diabetes medicine to blockbuster diet drug https://www.npr.org/2023/04/01/1166781510/ozempic-weight-loss-drug-big-business

Everyone wants the easy way out. I sometimes forget to eat but not because of a miracle drug. You wonder if those of us wanting to lose weight know you can’t stop taking this drug once you start it.

Patients discontinuing the use of weight-loss drugs such as Wegovy risk regaining their original body weight in about five years, a Novo Nordisk official said on Wednesday.

Novo Nordisk Says Stopping Obesity Drug May Cause Full Weight Regain in 5 Years–https://www.medscape.com/viewarticle/990267?src=rss

Side effects?

Just a few https://www.wegovy.com/taking-wegovy/side-effects.html

  • Possible thyroid tumors, including cancer.
  • Inflammation of your pancreas (pancreatitis)
  • Gallbladder problems
  • Increased risk of low blood sugar (hypoglycemia) in patients with type 2 diabetes, especially those who also take medicines for type 2 diabetes such as sulfonylureas or insulin
  • Kidney problems (kidney failure)
  • Serious allergic reactions
  • Change in vision in people with type 2 diabetes.
  • Increased heart rate
  • Depression or thoughts of suicide.

So if you want to lose weight by taking a GLP-1 receptor agonist remember the risks of side effects including the real possibility of having to take a drug that costs up to $1600.00 a month for the rest of your life.

Good luck with that. This joke’s on you.

Scary Charts – 02.06.23

/ SupremeCmdr / 3 Comments

To the extent that the Fed knows anything, it knows this, and really, really wants to force that blue line down into negative territory if possible. But it also knows that doing so will send prices spiraling out of control – which is another way of saying the dollar will crash (not necessarily against the euro and the yen, which have similar problems, but against oil, lumber, eggs, milk, cars, and all the other things voters buy regularly). The result? Political and financial chaos.

Welcome To the Death Spiral — https://rubino.substack.com/p/welcome-to-the-death-spiral

YIKES!

On a positive note I’ll likely be dead when the SHTF.

The Wind Chill Hit Minus 108 at New Hampshire’s Mount Washington — smithsonianmag.com

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The 6,288-foot summit endured record-breaking conditions brought by an Arctic air mass. The mountain in north-central New Hampshire stands 6,288 feet tall and often experiences dramatic weather. But meteorologists say this weekend’s powerful winds and chilly temperatures—which dipped to as low as minus 47 degrees—were unparalleled. The previous record-low wind chill at Mount Washington was minus 102.7 degrees in 2004.

The Wind Chill Hit Minus 108 at New Hampshire’s Mount Washington — Latest articles | smithsonianmag.com

Childhood Asthma, Gas Stoves and Junk Science

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Full Disclosure – I hate cooking on an electric stove. So there might be some bias in this post.

Here’s a link to the study behind the headlines – Population Attributable Fraction of Gas Stoves and Childhood Asthma in the United States https://www.mdpi.com/1660-4601/20/1/75#B6-ijerph-20-00075.

Here’s a nice review of the study that most people will never read – No, new study does not link gas stoves with asthma in children https://junkscience.com/2023/01/no-new-study-does-not-link–stoves-with-asthma-in-children/

I read the study behind the headlines:

Indoor gas stove use for cooking is associated with an increased risk of current asthma among children…
The proportion of children (<18 years old) exposed to gas stoves was obtained from the American Housing Survey for the US, and states with available data (n = 9). We found that 12.7% (95% CI = 6.3–19.3%) of current childhood asthma in the US is attributable to gas stove use. The proportion of childhood asthma that could be theoretically prevented if gas stove use was not present (e.g., state-specific PAFs) varied by state… Nonetheless, our results align with a cross-sectional study which found that the use of a gas stove or oven for heat was a main risk factor for doctor-diagnosed asthma in US children under age six [6].

Population Attributable Fraction of Gas Stoves and Childhood Asthma in the United States – link above

Note the authors went from “associated with” to “attributed to gas stove use”. When I got to the “main risk factor” statement I immediately went into WTF mode. So I decided to read some of the authors’ source documents including this one – Contribution of Residential Exposures to Asthma in US Children and Adolescents https://publications.aap.org/pediatrics/article-abstract/107/6/e98/66289/Contribution-of-Residential-Exposures-to-Asthma-in?redirectedFrom=fulltext.

The list of predictors of doctor diagnosed asthma included history of pet allergy, presence of pet in the household, dust mites, fungus, diagnosis of allergic rhinitis and cockroaches. The main risk factor of gas stove use is not listed.

Talor Gruenwald is listed as the lead author of the study causing an uproar from professional chefs in the US. Gruenwald used to work here https://rmi.org/ and now works here https://www.rewiringamerica.org

Power is in tearing human minds to pieces and putting them together again in new shapes of your own choosing.

George Orwell – 1984

This was an interesting deep dive behind the headlines.

Did I mention I hate cooking on an electric stove?

What Middle Class?

/ SupremeCmdr / 8 Comments

Hat tip to Mike Shedlock, a registered investment advisor at SitkaPacific Capital Management for highlighting the following video for his blog readers.

This is the portion of the blog post where I typically add a snarky comment.

Nope. Not going to joke about this.

News Addiction

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The results revealed that 16.5% of people surveyed showed signs of ‘severely problematic’ news consumption. Such individuals frequently became so immersed and personally invested in news stories that the stories dominated the individual’s waking thoughts, disrupted time with family and friends, made it difficult to focus on school or work, and contributed to restlessness and an inability to sleep.

73.6% of those recognized to have severe levels of problematic news consumption reported experiencing mental ill-being “quite a bit” or “very much” — whilst frequent symptoms were only reported by 8% of all other study participants.

61% of those with severe levels of problematic news reported experiencing physical ill-being “quite a bit” or “very much” compared to only 6.1% for all other study participants.

Taylor & Francis Group. “News addiction linked to not only poor mental wellbeing but physical health too, new study shows.” ScienceDaily. http://www.sciencedaily.com/releases/2022/08/220824102936.htm (accessed October 5, 2022).