FDA Announces Recall for Duloxetine

Nitrosamine impurities have prompted a number of drug recalls in recent years, including oral anticoagulants, metformin, and skeletal muscle relaxants.FDA Announces Recall of More than 7000 Bottles of Duloxetine – Medscape – October 28, 2024. – https://www.medscape.com/viewarticle/fda-announces-recall-more-than-7000-bottles-duloxetine

Depressing. But will be very depressing for people on this medication.

Enjoy Your Cruise (avoid the hot tub)

Legionnaires disease is a serious pneumonia caused by Legionella bacteria. Hot tubs can be a source of Legionella growth and transmission when they are inadequately maintained and operated. Private hot tubs on cruise ships are not subject to the same maintenance requirements as are public hot tubs in common areas. Lee S, Edens C, Ritter T, et al. Two Outbreaks of Legionnaires Disease Associated with Outdoor Hot Tubs for Private Use — Two Cruise Ships, November 2022–July 2024. MMWR Morb Mortal Wkly Rep 2024;73:950–954. DOI: http://dx.doi.org/10.15585/mmwr.mm7342a3

Would You Pay $850.00 a Month to Live in One of These?

The image above shows a proposed apartment in Denver, which would cost about $850 – less than half the current median rent in the city of $1,771. Are ‘micro-apartments’ converted from offices the answer to the housing crisis? https://www.usatoday.com/story/money/personalfinance/real-estate/2024/10/22/empty-offices-become-tiny-apartments-housing-crisis/75784459007/

I actually visited some micros in Providence RI.

One of the nation’s most beautiful historic shopping arcades was restored as 48 affordable micro-lofts, rents starting at $550 per month, and 17 small retail spaces in Providence, Rhode Island. The Micro Lofts at the Arcade Providence, completed in 2012, helps keep young professionals and artists downtown and is a major step in revitalizing the city. Micro Lofts at the Arcade Providence – https://www.cnu.org/what-we-do/build-great-places/micro-lofts-arcade-providence

If I were a lot younger, single, had a job in a CBD and not set in my Old Man Ways I would consider micro-living. I might even try a repurposed recycled wind turbine.

wind turbine tiny house

all images courtesy of Vattenfall and Business in Wind

During Dutch Design Week 2024, Superuse and Vattenfall showcase the discarded wind turbine part they’ve transformed into a furnished tiny house powered by solar panels. The design studio and energy company convert a nacelle, which is the top part of a wind turbine or the container of the engine, into a compact and movable furnished home, and visitors to the Dutch event can see it firsthand between October 19th and 27th, 2024, in Eindhoven. discarded wind turbine vessel turns into solar-powered tiny house by superuse and vattenfall — https://www.designboom.com/technology/superuse-vattenfall-discarded-wind-turbine-solar-powered-tiny-house-dutch-design-week-2024-10-24-2024/

I keep telling The Boss all I’m trying to do is to make our retirement income last as long as we last.

Rejected. Again.

Cannabis and Impaired Brain Development

The adolescent brain is particularly vulnerable to cannabis, especially today’s higher-potency products, which put teens at risk for impaired brain development; mental health issues, including psychosis; and cannabis use disorder (CUD).  That was the message delivered by Yasmin Hurd, PhD, director of the Addiction Institute at Mount Sinai in New York, during a May 6 press briefing at the American Psychiatric Association (APA) 2024 annual meeting. 

“We’re actually in historic times in that we now have highly concentrated, highly potent cannabis products that are administered in various routes,” Hurd told reporters. Tetrahydrocannabinol (THC) concentrations in cannabis products have increased over the years, from around 2%-4% to 15%-24% now, Hurd noted. High-Potency Cannabis Tied to Impaired Brain Development, Psychosis, CUD – Medscape – May 13, 2024. https://www.medscape.com/viewarticle/high-potency-cannabis-tied-impaired-brain-development-2024a1000935

Earlier posts on this topic:

Marijuana is Too Strong (THC turbocharged)

Cannabis Use and Psychosis Risk

Cannabis Use and Psychosis Risk (Aussie Version)

Reefer Madness

Diet and Your Immune System

Whereas nutrition scientists have conventionally studied the long-term impacts of loosely defined Mediterranean or Western diets, for example, today they have access to tools that allow them to zoom in on the short-term effects — both helpful and harmful — of narrower food groups and specific dietary components, and to probe the molecular mechanisms underpinning the effects of foods on immunity. Your diet can change your immune system — here’s how – https://www.nature.com/articles/d41586-024-03334-0

Nice article summarizing the latest research in diet and the immune system.

Alcohol and Nocturnal Leg Cramps (NLC)

I just discovered another reason to Drink Less Alcohol When You Get To My Age.

We identified an association between alcohol consumption and nocturnal leg cramps among patients aged 60 years and older attending general practices. These findings have implications for the prevention of cramps. Association Between Alcohol Consumption and Nocturnal Leg Cramps in Patients Over 60 Years Old: A Case-Control Study – https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6037509

Add this to the list of things that happen when you get older.