FDA Warns Against Combining Alcohol, Other CNS Depressants With Xyrem – AAFP News

According to the Dec. 17 statement, the FDA recently evaluated reports of patients who died while taking Xyrem — which is used to reduce instances of cataplexy and to manage other symptoms of narcolepsy — along with alcohol or other central nervous system (CNS) depressants. Although the precise cause of the deaths remains uncertain — the reports contained incomplete information and did not adequately address confounding factors, such as pre-existing sleep apnea and/or chronic obstructive pulmonary disease — given some of the circumstances noted in the deaths, the FDA determined that the recommendations in the Xyrem drug label should be strengthened to highlight the risks of using the drug in conjunction with CNS depressant drugs or alcohol.

via FDA Warns Against Combining Alcohol, Other CNS Depressants With Xyrem — AAFP News Now — AAFP.

Oops.

BBC News – Diabetes Fuels Heart Failure Risk

People with diabetes are up to 65% more likely to have heart failure, an analysis has found.

The National Diabetes Audit looked at data on almost two million people and also found increased risk of other complications, and premature death.

via BBC News – Diabetes fuels heart failure risk.

U-Shaped Link for BMI at DX With Mortality in DM2

U-Shaped Link for BMI at Diagnosis With Mortality in Type 2 Diabetes | insureintell.com.

CONCLUSIONS Patients categorized as normal weight or obese with T2DM within a year of diagnosis of T2DM exhibit variably higher mortality outcomes compared with the overweight group, confirming a U-shaped association of BMI with mortality. Whether weight-loss interventions reduce mortality in all T2DM patients requires study.

via The Association Between BMI Measured Within a Year After Diagnosis of Type 2 Diabetes and Mortality.

HT – Hank George

Simple Sit Test Predicts Long Life

This study evaluated the association between the ability to sit and rise from the floor with and without support and all-cause mortality in adults age 51 to 80.

There was a significant association between the use of more support to sit and rise from the floor and increasing all-cause mortality.

via Simple Sit Test Predicts Long Life.

Our profession typically uses chair-to-stand testing as part of a senior supplement.  Should we be considering the use of the sit-rise test instead?

jennovafoodblog's avatarjennovafoodblog

And I’m done exams, wohoo!! No more classes until January 7th :D! I really want to focus on my blog this Christmas break; I’ve got a few topics in mind before I start researching the suggested topics from some of you guys. If any of you have any requests, feel free to ask and I’ll make a list and eventually get to it :).

My roommate and I had our Christmas party last night, couldn’t have asked for a better group of people who came; it was a really nice reward after all of our exams :). After spending most of the day climbing (obviously), we came home and decorated the house with Christmas lights, homemade snowflakes and a cardboard Christmas tree I taped to the wall :P. I definitely feel the holiday spirit now, ready to get onto some vegan holiday creations!

Here’s a picture taken of me in…

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FDA Warns Chantix May Up Heart Risk

A meta-analysis ordered by the agency and conducted by drugmaker Pfizer found a higher occurrence of major adverse cardiovascular events — including death, MI, and stroke — with the drug than with placebo.

The FDA noted, however, that such events were uncommon in both groups, and the increased risk wasn’t statistically significant.

via Chantix May Up Heart Risk, FDA Warns.

Quitting smoking is good.  Maybe quitting smoking without a pharmaceutical assist is better.  Additional link to the FDA release follows.

Safety Alerts for Human Medical Products > Chantix (Varenicline): Safety Communication – Updated Safety Review On The Risk of Cardiovascular Adverse Events.