When the rules are broken, never play by the rules.
via The Economic Roots of Your Life Crisis – Umair Haque – Harvard Business Review.
Author: SupremeCmdr
How to Completely, Utterly Destroy an Employee’s Work Life
How to completely, utterly destroy an employee’s work life – The Washington Post.
HT John Hollon
Not a complete How To Manual but a good starting point nonetheless.
DM Risk – White Rice Bad
Eating more white rice may up the risk of type 2 diabetes, especially for Asian populations, researchers said.Patients who ate the greatest amounts of the grain had a 27% greater risk of developing the disease than those who ate the least, and the relative risk was higher among Asian patients, Qi Sun, PhD, of Harvard, and colleagues, reported in BMJ.
This is very bad news for Chinese take out businesses.
Spider Angioma — NEJM Images in Clinical Medicine
Compression of the central arteriole caused the entire lesion to blanch, and it quickly refilled once the compression was released This pattern of blanching and refilling characterizes spider angiomas, which are suggestive of liver disease.
For the underwriter who always wondered what one of these things looks like. For the geekiest underwriters, click on and take a look at the video. And for the underwriter who thinks she should have a Medical Doctor, the following is from the NEJM Resident E-Bulletin of 02.23.12.
Clinical Pearls
- What is the differential diagnosis of a subacute confusional state in a patient with liver disease?
The differential diagnosis includes five major syndromes: hepatic encephalopathy, Wernicke’s encephalopathy, alcohol withdrawal, occult seizures, and infection. Hepatic encephalopathy refers to an alternation in cognitive function that is secondary to a metabolic process caused by liver failure. Wernicke’s encephalopathy refers to the triad of gait ataxia, ophthalmoplegia and confusion caused by thiamine deficiency, commonly seen in chronic alcoholics. Alcohol withdrawal, occult seizures, and underlying infection may also cause a subacute confusional state in a patient with chronic liver disease.
Independent Contractors Helping to Shape the New World of Work
Of 530 recently surveyed independent consultants, more than 80 percent expressed satisfaction with their employment status, although 27 percent admitted that, given the chance, they would return to a full-time job.
via Independent Contractors Helping to Shape the New World of Work – Featured Article – Workforce.
The Doctor Is Out: Young Talent Is Turning Away From Primary Care
Link posted without further comment. A must read article.
Circulating TNF Receptors 1 and 2 Predict ESRD in Type 2 Diabetes
Glass of Wine Eases Stroke Risk in Women
A study of more than 80,000 women found that low to moderate alcohol consumption was associated with a 17% to 21% reduction in risk of stroke.
Minor Trauma Led to Death in Pradaxa Patient
Dabigatran etexilate is an oral anticoagulant that acts as a direct, competitive thrombin inhibitor. It does not require routine monitoring and has been approved by the FDA for the prevention of stroke and systemic embolism in patients with atrial fibrillation. Note, however, that no effective reversal agent for dabigatran in the event of catastrophic hemorrhage has been identified.
On the article’s webpage you’ll find a link to download a PDF copy of the source article.
Mortality Risk Quantified for Diabetes Plus Kidney Disease
This meta-analysis found that the presence of chronic kidney disease strongly predicted mortality risk in patients with type 2 diabetes. Chronic kidney disease more than doubles mortality risk in patients with type 2 diabetes, researchers found. In an analysis of nearly two dozen randomized controlled trials involving diabetic patients, the highest mortality rates were observed in those trials that required the inclusion of patients with renal disease, according to Marc Pfeffer, MD, PhD, of Brigham and Women’s Hospital in Boston, and colleagues. Trials that selected for patients with elevated serum creatinine or impaired estimated glomerular filtration rate eGFR had mortality rates of 5.9 to 8.2 per 100 patient-years, whereas the rest of the trials had rates no higher than 3.3, the researchers reported online in the Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease.
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