Conclusion: Hepatic steatosis is associated with a greater intake of fat and fried foods, whereas visceral obesity is associated with increased consumption of sugar and reduced consumption of fiber in overweight and obese adolescents at risk of type 2 diabetes. This study was registered at clinicaltrials.gov as NCT00755547.
diabetes
Yogurt and Diabetes
Eating yogurt can reduce the risk of getting Type 2 diabetes by 28 percent, compared with consuming none, according to a study published today by Diabetologia. Higher consumption of low-fat fermented dairy products, such as yogurt and some cheeses, also lowered the relative risk of diabetes by 24 percent overall, the study showed.
via Yogurt May Be an Ally in Fight Against Diabetes: Study – Bloomberg.
Update 03.28.14
I’ve started eating yogurt every day.
Body-Mass Index and Mortality among Adults with Incident Type 2 Diabetes — NEJM
Conclusions
We observed a J-shaped association between BMI and mortality among all participants and among those who had ever smoked and a direct linear relationship among those who had never smoked. We found no evidence of lower mortality among patients with diabetes who were overweight or obese at diagnosis, as compared with their normal-weight counterparts, or of an obesity paradox.
via Body-Mass Index and Mortality among Adults with Incident Type 2 Diabetes — NEJM.
Farxiga (dapagliflozin) – Think Diabetes
The FDA has approved dapagliflozin (Farxiga) for treatment of type 2 diabetes in adults, along with diet and exercise, the agency said in a statement.
The approval comes with strings, however: drugmakers Bristol-Myers Squibb and AstraZeneca must conduct six post-market studies, which include a cardiovascular outcomes trial in patients with baseline cardiovascular disease risks, a bladder cancer risk trial, an animal study looking at drug-induced urinary flow and bladder tumor promotion, two trials on risks in pediatric patients, and an enhanced pharmacovigilance program to study liver abnormalities and pregnancy outcomes.
Mediterranean Diet Cuts Risk of Diabetes
Compared with a control diet and a Mediterranean diet supplemented with mixed nuts, the olive oil-supplemented Mediterranean diet was associated with a 40% lower likelihood for new-onset diabetes (HR 0.60, 95% CI 0.43-0.85) , according to Jordi Salas-Salvado, MD, PhD, of the Universitat Rovira i Virgili in Reus, Spain, and colleagues.
Dieters who consumed a nut-supplemented Mediterranean diet did not see such protective benefits (HR 0.82, 95% CI 0.61-1.10), they wrote online in the Annals of Internal Medicine.
via Mediterranean Diet Cuts Risk of Diabetes.
Read the article and then the readers’ comments. The following are some excerpts:
The findings of this study identify inherent weaknesses in methodology. The low fat control group did not adhere to a low fat diet and the improbable risks of CVD were notably higher.
I wonder if the researchers would consider the benefits of asking their subjects to spread their food intake more evenly throughout the day rather than the the usual Spanish pattern of negligible breakfast, snack about 11, then large lunch mid-afternoon and a big, late evening meal. Also in my experience travelling in various parts of Spain, the diet includes plenty of pork.’Every bit of the pig but the eyes.’.
The olive oil group was probably using that in place of other vegetable oils for cooking and salad. Vegetable oils like soy and corn oil are high in pro-inflammatory omega-6, and are often partially hydrogenated (ie trans fats.) Avoidance of these in the olive group could have made a difference.
Be cautious in coming to conclusions based upon this study. The sample size was small. Perhaps too little attention was paid to what the participants did not consume. We all know less red meat is better for health. The Mediterranean style diet is clearly a healthy diet but I’m not quite ready to attribute all the wonderful benefits to the diet alone.
Think lifestyle. Despite the increase in US style fast food restaurants in Spain, the overall dietary preference continues to be a Mediterranean diet. So how much of the study’s effect come from fast food avoidance?
BTW, yesterday was a totally Mediterranean day for me. Veggie pizza for lunch and a Greek salad with grilled chicken for dinner.
Dairy Consumption, Type 2 Diabetes, and Changes in Cardiometabolic Traits: A Prospective Cohort Study of Middle-Aged and Older Chinese in Beijing and Shanghai
CONCLUSIONS: Dairy consumption was associated with a significantly lower risk of type 2 diabetes and favorable changes of cardiometabolic traits in Chinese.
What about non-Chinese? Good news for me though.
Ice cream.
Long-Term Complications and Mortality in Young-Onset Diabetes
CONCLUSIONS – Young-onset T2DM is the more lethal phenotype of diabetes and is associated with a greater mortality, more diabetes complications, and unfavorable cardiovascular disease risk factors when compared with T1DM.
via Long-Term Complications and Mortality in Young-Onset Diabetes.
HbA1c and the Risks for All-Cause and Cardiovascular Mortality in the General Japanese Population
High HbA1c levels were associated with increased risk for all-cause mortality and death from CVD, coronary heart disease, and cerebral infarction in general East Asian populations, as in Western populations.
via HbA1c and the Risks for All-Cause and Cardiovascular Mortality in the General Japanese Population.
Subarachnoid Hemorrhage in Type 1 Diabetes
The incidence of nonaneurysmal SAH is high among patients with type 1 diabetes. Our findings suggest that nonaneurysmal SAH is a distinct new microvascular complication in type 1 diabetes.
Obstructive Sleep Apnea and Diabetic Nephropathy
OSA is independently associated with DN in type 2 diabetes. eGFR declined faster in patients with OSA. Nitrosative stress may provide a pathogenetic link between OSA and DN. Interventional studies assessing the impact of OSA treatment on DN are needed.
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