Medical News: HbA1c Predicts Cardiovascular Risk – in Cardiovascular, Diabetes from MedPage Today
diabetes
Globalization of Diabetes
Abstract
Type 2 diabetes is a global public health crisis that threatens the economies of all nations, particularly developing countries. Fueled by rapid urbanization, nutrition transition, and increasingly sedentary lifestyles, the epidemic has grown in parallel with the worldwide rise in obesity. Asia’s large population and rapid economic development have made it an epicenter of the epidemic. Asian populations tend to develop diabetes at younger ages and lower BMI levels than Caucasians. Several factors contribute to accelerated diabetes epidemic in Asians, including the “normal-weight metabolically obese” phenotype; high prevalence of smoking and heavy alcohol use; high intake of refined carbohydrates (e.g., white rice); and dramatically decreased physical activity levels. Poor nutrition in utero and in early life combined with overnutrition in later life may also play a role in Asia’s diabetes epidemic. Recent advances in genome-wide association studies have contributed substantially to our understanding of diabetes pathophysiology, but currently identified genetic loci are insufficient to explain ethnic differences in diabetes risk. Nonetheless, interactions between Westernized diet and lifestyle and genetic background may accelerate the growth of diabetes in the context of rapid nutrition transition. Epidemiologic studies and randomized clinical trials show that type 2 diabetes is largely preventable through diet and lifestyle modifications. Translating these findings into practice, however, requires fundamental changes in public policies, the food and built environments, and health systems. To curb the escalating diabetes epidemic, primary prevention through promotion of a healthy diet and lifestyle should be a global public policy priority.
© 2011 by the American Diabetes Association. Reproduced on this blog under a Creative Commons license. Source attribution is provided via link.
DM Increases Cancer Risk
Diabetes Increases Risk of Cancer Death – NYTimes.com
“Researchers from the National Cancer Institute collected diet, lifestyle and health data from 500,000 people ages 50 to 71 and followed the patients for 11 years. They found that having diabetes was associated with an 11 percent increased risk of dying from cancer among women and a 17 percent increased risk of cancer death among men.”
Duration of Diabetes Increases MI Risk
In Men, Duration of Diabetes Linked to Raised Heart Risk
“Risk rose along with duration of disease — compared to men without diabetes, men who had early-onset diabetes (in this case, for an average of 17 years or more) had 2.5 times the risk of a heart attack. That level of risk was equal to that of men with a prior history of heart attack, the team noted.”
Fatty Liver = Increased DM2 Risk
Fatty liver increases risk for type 2 diabetes
“Individuals with fatty liver are five times more likely to develop type 2 diabetes then those without fatty liver, researchers have found. This increased risk occurred regardless of the patient’s fasting insulin levels, which were used as a marker of insulin resistance in the study”
DM2 Dietary Guidelines
Diabetes diet – type 2: MedlinePlus Medical Encyclopedia
I’m not diabetic but I have a strong family history of the disease so I try to eat like a diabetic.
Well, most of the time.
DM and Depression – Watch That Combo
In Women, Diabetes Plus Depression a Deadly Combo
Women who had diabetes had about a 35 percent increased risk of dying, and those with depression had about a 44 percent increased risk, compared with women with neither condition, the researchers calculated.
Those with both conditions had about twice the risk of dying, the study authors found.
DM1 Mortality Rate Improves
Type 1 Diabetes Death Rate is Falling, But Not Fast Enough
When the researchers broke the mortality rate down by the time of diagnosis, they found that those diagnosed later had a much improved mortality rate. The group diagnosed in the 1960s had a 9.3 times higher mortality rate than the general population, while the early 1970s group had a 7.5 times higher mortality than the general population. For the late 1970s group, mortality had dropped to 5.6 times higher than the general population.
Look AHEAD Clinical Trial
Hypoglycemia in DM2 = Higher Mortality Risk
Type 2 diabetes patients who experienced these serious drops in blood glucose had nearly three times the risk of death and twice the risk of a major macrovascular event compared with those who didn’t experience hypoglycemia, Sophia Zoungas, MD, PhD, of the University of Sydney in Australia, and colleagues reported in the New England Journal of Medicine.
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