Remission of type 2 diabetes was generally infrequent in routine care settings but may be a reasonable goal for a subset of people who lose a significant amount of weight shortly after diagnosis.
Incidence and Characteristics of Remission of Type 2 Diabetes in England: A Cohort Study Using the National Diabetes Audit – Diabetes Care 2022;45(5):1151–1161
https://doi.org/10.2337/dc21-2136
Diet and Disease
Just Another Hump Day…Sweet
Scientists have demonstrated that normal brain aging is accelerated by approximately 26% in people with progressive type 2 diabetes compared with individuals without the disease.
eLife. “Type 2 diabetes accelerates brain aging and cognitive decline.” ScienceDaily. http://www.sciencedaily.com/releases/2022/05/220525080527.htm (accessed May 25, 2022)
Makes you wonder if improving your diet will help.
Many adults can achieve remission of type 2 diabetes with a primary intervention consisting of a diet that emphasizes whole, plant-based foods, according to a new publication from the American College of Lifestyle Medicine (ACLM).
Experts Endorse Plant-Based Diet for Type 2 Diabetes Remission — https://www.medscape.com/viewarticle/974591?src=rss#vp_1
But we all know how hard lifestyle changes can be. Maybe best to just listen to some music.
Bifidobacterium longum 35624
Probiotic Improves Symptoms of Irritable Bowel Syndrome – Medscape – May 09, 2022 —https://www.medscape.com/viewarticle/973643?src=rss#vp_1
Eat yogurt.
Thinking About Retirement (or just another fine Saturday Morning)
Andel’s suggestion to anyone contemplating retirement: “Find a new routine that’s meaningful.” He points to people living in the Blue Zones, regions of the world that have been identified to be home to a greater number of residents who’ve reached the age of 100 and beyond. One of the common characteristics among Blue Zone inhabitants is, says Andel, “these people all have purpose.”
Think Retirement Is Smooth Sailing? A Look at Its Potential Effects on the Brain — https://getpocket.com/read/2840794990
The funny thing about life at “retirement age” and still working is you think about retirement a lot.
Since I still work a full time job I have a lot of trouble envisioning what my retirement will look like.
After reading this article and listening to Andel’s short talk I am now scared of retirement.
I need to figure out how to avoid brain rot. But my journal tells me I already have.
My Purpose is to educate others on diet and disease, weight loss and weight management by sharing my personal journey through writing and other teaching activities.
Stay as Thin as You Can as Long as You Can
Based on the evidence from clinical trials weight loss (typically 15 kg or greater) is the main driver and predictor of remission.
Dietary strategies for remission of type 2 diabetes: A narrative review — https://doi.org/10.1111/jhn.12938
A weight loss program can lead to type 2 diabetes remission, even in individuals with a normal body mass index (BMI), via loss of body fat, particularly in the liver and pancreas, shows a UK study.
Type 2 Diabetes Remission Possible For Those With Lower BMI — https://www.medscape.com/viewarticle/971599?src=rss#vp_1
The title of this post is a direct quote from an Endocrinologist who at the time was practicing in Dallas Texas. I asked if he had any advice for me to reduce my risk of developing diabetes.
“Stay as thin as you can as long as you can.”
These words have stuck with me ever since.
The App That Helps Me Be a More Patient Centered Physician — A Country Doctor Writes:
One of the most rewarding things I do in my clinic happens on my iPhone. When I sit down with a middle aged patient to talk about their cardiovascular risk, I open the risk calculator created by the American Heart Association and the American College of Cardiology. I talk my way through as I enter […]
The App That Helps Me Be a More Patient Centered Physician — A Country Doctor Writes:
The risk calculator is quite useful but I re-blogged this post for its link to the Hale study, which was news to me. This study published in 2004 showed older people between the ages of 70 and 90 who followed a Mediterranean diet have 50% lower rate of all-cause and cause-specific mortality than people who dine on the SAD Western diet. The four primary risk factors were diet, moderate alcohol intake, physical activity, and non-smoking.
Lifestyle matters.
Diet Quality and Covid-19 Risk/Severity
Poor metabolic health and unhealthy lifestyle behaviors have been associated with higher risk and severity of COVID-19.
A dietary pattern characterized by healthy plant-based foods was associated with lower risk and severity of COVID-19.
We found evidence of a synergistic association of poor diet and increased socioeconomic deprivation with COVID-19 risk that was higher than the sum of the risk associated with each factor alone.
Merino J, Joshi AD, Nguyen LH, et al
Diet quality and risk and severity of COVID-19: a prospective cohort study
Gut 2021;70:2096-2104. — https://gut.bmj.com/content/70/11/2096
In six countries, plant-based diets or pescatarian diets were associated with lower odds of moderate-to-severe COVID-19. These dietary patterns may be considered for protection against severe COVID-19 In 2884 front-line healthcare workers from six countries (France, Germany, Italy, Spain, UK, USA), individuals who reported following plant-based diets and plant-based diets or pescatarian diets that were higher in vegetables, legumes and nuts, and lower in poultry and red and processed meats, had 73% and 59% lower odds of moderate-to-severe COVID-19, respectively.
Kim H, Rebholz CM, Hegde S, et al. Plant-based diets, pescatarian diets and COVID-19 severity: a population-based case–control study in six countries
BMJ Nutrition, Prevention & Health 2021;4:doi: 10.1136/bmjnph-2021-000272 — https://nutrition.bmj.com/content/4/1/257
Eat your vegetables!
Diet-induced Alteration of Intestinal Stem Cell Function (in mice)
“The first thing we noticed was that the small intestine increases greatly in size on the high-calorie diet,” says study leader Anika Böttcher. “Together with Fabian Theis’ team of computational biologists at Helmholtz Munich, we then profiled 27,000 intestinal cells from control diet and high fat/high sugar diet-fed mice. Using new machine learning techniques, we thus found that intestinal stem cells divide and differentiate significantly faster in the mice on an unhealthy diet.” The researchers hypothesize that this is due to an upregulation of the relevant signaling pathways, which is associated with an acceleration of tumor growth in many cancers. “This could be an important link: Diet influences metabolic signaling, which leads to excessive growth of intestinal stem cells and ultimately to an increased risk of gastrointestinal cancer,” says Böttcher.
Helmholtz Zentrum München – German Research Center for Environmental Health. “New link between diet, intestinal stem cells and disease discovered.” ScienceDaily. http://www.sciencedaily.com/releases/2021/11/211119155604.htm (accessed November 27, 2021).
I wonder what Dr. Lustig would say about this study?
Dr. Robert Lustig – The Sugar Pandemic – 2012 Presentation at Yale University and Dr. Robert Lustig on Sugar.
MIND Your Diet
MIND diet is associated with better cognitive functioning independently of brain pathology, suggesting that the MIND diet may contribute to cognitive resilience in older adults.
Dhana, Klodian et al. ‘MIND Diet, Common Brain Pathologies, and Cognition in Community-Dwelling Older Adults’. 1 Jan. 2021 : 683 – 692. — https://content.iospress.com/articles/journal-of-alzheimers-disease/jad210107
So, what is the MIND diet?
The traditional Mediterranean dietary pattern includes mainly whole, minimally processed plant foods including cereal grains, legumes, vegetables, fruit, nuts, and fish with small amounts of meat, milk, and dairy products and a regular modest amount of alcohol.4 The DASH diet emphasizes fruit, vegetables, and low-fat dairy products and includes whole grains, poultry, fish, and nuts, and is reduced in fats, red meat, sweets, and sugar-containing beverages.4 Combining the two diets, the MIND diet emphasizes natural, plant-based foods, specifically promoting an increase in the consumption of berries and green leafy vegetables, with limited intakes of animal-based and high saturated fat foods.
What Are the Components to the MIND Diet? — https://jandonline.org/article/S2212-2672(15)01251-4/fulltext
I became aware of the MIND diet earlier this year. It’s nice to know my dietary pattern has a name.
My Hemoglobin A1C is (fill in the blank)
Citation
Jonas DE, Crotty K, Yun JDY, et al. Screening for Prediabetes and Type 2 Diabetes: Updated Evidence Report and Systematic Review for the US Preventive Services Task Force. JAMA. 2021;326(8):744–760. doi:10.1001/jama.2021.10403
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