Rising Despair

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ajph.2019.305002f3

Cross-Sectional Weighted Prevalence of Despair by Race/Ethnicity and Education: United States, 2016–2017

Note. HS = high school. The figure shows results for wave V of the study. The average age was 37 years. Non-Hispanic White with high school or less education was the reference category. We conducted a χ2 test of independence to compare proportions in each group to the reference category. *P < .05; **P < .01; ***P < .001.

The Depths of Despair Among US Adults Entering Midlife

Conclusions. Results suggest that generally rising despair among the young adult cohort now reaching midlife that cuts across racial/ethnic, educational, and geographic groups may presage rising midlife mortality for these subgroups in the next decade.

Our study had potential limitations. We measured despair using several indicators of mental and emotional health and substance use. These indicators do not completely capture all domains of despair; for example, we were unable to account for economic anxiety, reports of physical pain, or hopelessness. We did not examine mortality.

Still Not a Vegan

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Diet rich in animal protein is associated with a greater risk of early death

Heli E K Virtanen, Sari Voutilainen, Timo T Koskinen, Jaakko Mursu, Petra Kokko, Maija P T Ylilauri, Tomi-Pekka Tuomainen, Jukka T Salonen, Jyrki K Virtanen. Dietary proteins and protein sources and risk of death: the Kuopio Ischaemic Heart Disease Risk Factor Study. The American Journal of Clinical Nutrition, 2019; DOI: 10.1093/ajcn/nqz025

Marta Guasch-Ferré, Ambika Satija, Stacy A. Blondin, Marie Janiszewski, Ester Emlen, Lauren E. O’Connor, Wayne W. Campbell, Frank B. Hu, Walter C. Willett, Meir J. Stampfer. Meta-Analysis of Randomized Controlled Trials of Red Meat Consumption in Comparison With Various Comparison Diets on Cardiovascular Risk Factors. Circulation, 2019; 139 (15): 1828 DOI: 10.1161/CIRCULATIONAHA.118.035225

Want to Keep That Weight Off? (give up computers, video games, and television)

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In the years following bariatric surgery, a person’s overall eating behaviors and the amount of time spent watching television, playing video games and using a computer for recreation are a better indication of long-term weight loss success than specific weight control practices like counting calories.

Reducing sedentary behavior; avoiding fast food; addressing problematic eating behaviors — including eating continuously, eating when full, loss of control and binge eating; and promoting self-weighing at least weekly were all behavioral targets the research team identified that patients should strive for and doctors should promote as part of post-surgical patient care.

Analysis identifies patients most at risk for weight regain after bariatric surgery

Lock them up — RadaJonesMD

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Last night, the heated debate on vaccination reached a boiling point. On March 26, 2019, in Rockland County, NY, unvaccinated children were barred from public places. Not only schools. Restaurants, supermarkets, worship places. They’re practically on house arrest. What about doctor’s offices and the ER? I don’t know. This is unprecedented. Rockland County is a 300K…

via Lock them up — RadaJonesMD

Long-term Effects of Metformin on Diabetes Prevention: Identification of Subgroups That Benefited Most in the Diabetes Prevention Program and Diabetes Prevention Program Outcomes Study

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CONCLUSIONS – Metformin reduces the development of diabetes over 15 years. The subsets that benefitted the most include subjects with higher baseline fasting glucose or HbA1c and women with a history of GDM.

You can access the abstract and full study online at this link to the Diabetes Journal.

The commentary article at this link is also an interesting read.

More Evidence for a Prevention-Related Indication for Metformin: Let the Arguments Resume!

Dual Receipt of Prescription Opioids From the Department of Veterans Affairs and Medicare Part D and Prescription Opioid Overdose Death Among Veterans: A Nested Case–Control Study

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Among veterans enrolled in VA and Part D, dual use of opioid prescriptions was independently associated with death from prescription opioid overdose. This risk factor for fatal overdose among veterans underscores the importance of care coordination across health care systems to improve opioid prescribing safety.

Full abstract at this link.