FDA Okays Naloxegol Movantik in Opioid-Induced Constipation

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If you read the source article you’ll never look at constipation the same way ever again. Better dig deeper to find out why your applicant is constipated.  It may not be just a horrible diet and lack of dietary fiber.

And yet another FDA approved drug to counteract adverse effects from another FDA approved drug.

FDA Okays Naloxegol Movantik in Opioid-Induced Constipation.

The US Food and Drug Administration (FDA) has approved naloxegol (Movantik, AstraZeneca Pharmaceuticals), a peripherally acting opioid receptor antagonist, for the treatment of opioid-induced constipation (OIC) in adults with chronic noncancer pain.

OIC is a common adverse effect of opioid use. An estimated 40% to 80% of patients receiving long-term opioid therapy experience OIC, which can be severe enough to cause discontinuation of opioid therapy.

British pair found murdered on Thai resort

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British pair found murdered on Thai resort.

“It was the first time this has happened on the island. I have never seen anything like this,” the staff member added, requesting anonymity.


No, it is not the first time.  See second article.

British tourists ‘murdered’ in Thailand: The sinister streak lurking beneath seeming paradise – News & Advice – Travel – The Independent.

Their deaths take to 13 the number of British visitors to Thailand murdered in the past five years in what the Foreign Office calls “vicious, unprovoked attacks by gangs”.

FDA Approves Bupropion/Naltrexone Contrave for Obesity

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FDA Approves Bupropion/Naltrexone Contrave for Obesity.

If I’m understanding this correctly we now have an anti-depressant combined with a drug originally approved for treating opioid, then alcohol addiction, approved by the FDA to treat obesity.

This will be interesting.

UPDATE

Obesity drugs have side effects. The reason it’s taken three years for the FDA to approve NB32/Contrave is that obesity drugs have serious side effects. So serious, in fact, that several major diet drugs have been yanked from the market, making doctors, regulators and yes, investors shy away. Cardiovascular disease and mood problems are just two of the potentially serious side effects associated with Qsymia and Belviq. Older drugs Xenical  and Alli carry a risk of permanent liver and kidney damage.  And those weight loss supplements you buy over the counter? Some are deadly.

via Contrave: Is This The Weight Loss Drug We’ve Been Waiting For?.

Like I said, this will be interesting.

Hypochondriasis (Part 2)

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Priceless.

notdeaddinosaur's avatarMusings of a Dinosaur

Even paranoids have enemies [citation needed]* and even hypochondriacs get sick.

I have a patient who is a full blown hypochondriac sufferer of health anxiety. He firmly believes he has full-blown AIDS after a single extramarital sexual contact (non-genital) one month prior with a woman not known to have HIV. (Reality check: the other person didn’t have HIV, the specific contact as described was ridiculously unlikely to have transmitted the virus had it been present, and AIDS takes months to years to develop after actual HIV infection.) He once believed his kitchen counters were radioactive because of a news reports of toxic spillage into a creek next to his housing development. He was also concerned about having inhaled particles of styrofoam doing a project with his kid, which then made their way through through his body and were coming out in his saliva. In short, he has it bad.

But he called a few weeks…

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Senior Life Insurance Underwriter – Job Positions Available – Elite Sales Processing INC

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Senior Life Insurance Underwriter

 Elite Sales Processing, Inc. (ESP) a highly recognized National Insurance Services TPA provider located in Omaha, Nebraska has an immediate need for Full Time Senior Life Insurance Underwriters. Home Office or Remote positions are available.

These positions are available immediately.

 Requirements:

  •  10 years senior life insurance underwriting experience.
  • Current approval limits $2,000,000 plus and up to Table 16
  • Brokerage – Sub-Standard Experience required.
  • Financial underwriting experience.
  • Strong Human relations and communication skills.
  • FLMI or FALU preferred but not required.
  • Ability to work quickly and efficiently with an automated work flow system.
  • Strong knowledge of MIB, Privacy laws and Insurance Compliance regulations.

Please send resume to Tom Gracey, Chairman/Chief Underwriting Officer, tgracey@espsvcs.com and/or call direct @ 888-545-5490.