Effect of Aspirin on Vascular and Nonvascular Outcomes Meta-analysis

Conclusion: Despite important reductions in nonfatal MI, aspirin prophylaxis in people without prior CVD does not lead to reductions in either cardiovascular death or cancer mortality. Because the benefits are further offset by clinically important bleeding events, routine use of aspirin for primary prevention is not warranted and treatment decisions need to be considered on a case-by-case basis.

via Arch Intern Med — Abstract: Effect of Aspirin on Vascular and Nonvascular Outcomes: Meta-analysis of Randomized Controlled Trials, February 13, 2012, Seshasai et al. 172 3: 209.

Latin America: Where the world’s jobs are

Latin America: Where the world’s jobs are – CSMonitor.com.

So far, 200 entrepreneurs from 30 different countries have traveled to Chile to try to get their ideas off the ground through Start-Up Chile. The program aims to fund 1,000 entrepreneurs by 2014, and not only benefits the grantees – 80 percent of whom are foreigners – but is a boon to Chile, too, says spokeswoman Brenna Loury.

Interesting little article that offers minimal facts to back up the author’s assertion in the title.  How does 200 entrepreneurs equal “where the world’s jobs are”?

No Age Limit on Benefits of Eating Well

Older people who eat properly are likely to live longer.

That’s the implication of a study looking at mortality and eating habits among a cohort of nearly 4,000 people 65 and older, according to Luis Afonso, MD, of Wayne State University in Detroit, and colleagues.

After an average follow-up of 13 years, participants with a good diet had lower rates of all-cause and cardiovascular mortality, compared with those who had a poor diet, Afonso and colleagues reported in the Feb. 13 issue of Archives of Internal Medicine.

via Medical News:No Age Limit on Benefits of Eating Well – in Primary Care, Diet & Nutrition from MedPage Today.

I’ll take fries with that.

Biomarkers May Help Heart Failure Risk Prediction

After accounting for the clinical risk score, several echocardiographic findings were independently associated with incident heart failure HRs 1.11 to 2.91, P≤0.001 for all:

  • Reduced left ventricular ejection fraction
  • Abnormal mitral inflow E/A peak velocity ratio a measure of diastolic function
  • Enlarged left atrium Increased left ventricular mass

These variables were used to create an echocardiographic score.Elevated levels of NT-proBNP also were independently associated with heart failure risk HR 1.61 as a continuous variable and HR 2.7 for values greater than 190 pg/mL, P

via Medical News:Biomarkers May Help Heart Failure Risk Prediction – in Cardiovascular, CHF from MedPage Today.

Patient Access to Core Attributes of Primary Care Linked to Lower Mortality

Specifically, authors of “Primary Care Attributes and Mortality: A National Person-Level Study” found that patients who reported three attributes in their usual source of care — comprehensiveness, patient-centeredness and enhanced access — had lower mortality during up to six years follow-up than patients reporting less access to those three attributes.

via Patient Access to Core Attributes of Primary Care Linked to Lower Mortality — AAFP News Now — American Academy of Family Physicians.

A Harrison Barnes – Do What You Want To Do, Not What You Think You Should Do

If you have a job or are pursuing a certain career primarily because you think you should, or because others think you should, you are making a huge mistake. You need to understand that if you keep doing this, you are never going to be truly happy. You need to be living the life and having the career that makes you happy. The voices that you hear inside yourself, which tell you to pursue a certain profession or be a certain thing, are often not your own voice. They are the voices of your parents; they are the voices of your peers in school; they are the voices of the people you associate with at work.

via Job Search Guru | A Harrison Barnes, Career Advice, Job Search, Change In Profession | Harrison Barnes | Try the Career Coaching Club!.

Why do you do what you do?  Easy question but sometimes you may not like the answer.