Low-Carbohydrate Diets and All-Cause and Cause-Specific Mortality — Ann Intern Med
Conclusion: A low-carbohydrate diet based on animal sources was associated with higher all-cause mortality in both men and women, whereas a vegetable-based low-carbohydrate diet was associated with lower all-cause and cardiovascular disease mortality rates.
I stumbled across this article while evaluating a persistent CPK elevation in an applicant with HLD and other CHD risk factors.
There are three links in this article to the original comparative effectiveness review, a clinician guide, and a consumer guide.
Good training stuff for your newbies.
BBC News – Today – Calcium supplement effectiveness ‘pretty poor’
Here’s a pretty good interview on the calcium supplementation and MI risk for those of you who like to listen and learn.
Calcium supplementation appears to increase the risk of myocardial infarction, a meta-analysis showed.
Among studies of patients with or at risk for osteoporosis, those who took calcium supplements were about 30% more likely to have an MI than those who did not, Ian Reid, MD, of the University of Auckland in New Zealand, and colleagues reported online in BMJ.
Among randomized controlled trials with patient-level data, the hazard ratio for MI with supplementation was 1.31 (95% CI 1.02 to 1.67). Among those with trial-level data, the relative risk was 1.27 (95% CI 1.01 to 1.59).
Glycemic Control and Cardiovascular Disease in 7,454 Patients With Type 1 Diabetes — Diabetes Care
CONCLUSIONS This observational study of patients in modern everyday clinical practice demonstrates progressively increasing risks for CHD and CVD with higher A1C, independently of traditional risk factors, with no J-shaped risk curves. A baseline mean A1C of 7.2% showed considerably reduced risks of CHD and CVD compared with A1C 9.0%, emphasizing A1C as a strong independent risk factor in type 1 diabetes.
On-the-job pressure significantly increases the likelihood that women will develop ischemic heart disease, a large Danish study found.
Compared with women who felt their workplace pressure was suitable, those who reported that the pressure was much too high had a nearly 50% increased risk of developing ischemic heart disease (HR 1.47, 95% CI 1.14 to 1.88), according to Karen Allesøe, PhD, and colleagues from Glostrup University Hospital.
Conclusion: In this multi-ethnic cohort, addition of CACS to a prediction model based on traditional risk factors significantly improved the classification of risk and placed more individuals in the most extreme risk categories.
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