The study included information from 135 randomized trials — 55 with a placebo control and 80 with an active comparator — that included a total of 246,955 participants with or without cardiovascular disease. The study initially included trials of atorvastatin, fluvastatin, simvastatin, lovastatin, pravastatin, and rosuvastatin (Crestor); trials of pitavastatin (Livalo) were added post hoc because the protocol was already being finalized at the time the drug was approved.
CHD risk factors
Cardiovascular Risk Factors in CKD Associate with Both ESRD and Mortality
Cardiovascular Risk Factors in CKD Associate with Both ESRD and Mortality.
Link above is to the JASN abstract. Link below is the AHA Life’s Simple 7 initiative.
PTSD May Raise Risk of Heart Disease
Through a median of 13 years of follow-up, twins who had PTSD at baseline had a significantly higher rate of incident coronary heart disease compared with those without PTSD (22.6% versus 8.9%), according to Viola Vaccarino, MD, PhD, of Emory University in Atlanta, and colleagues.
The difference was not due to established risk factors, since the association remained significant after adjustment for sociodemographic factors, service in Southeast Asia, lifestyle factors, coronary heart disease risk factors, major depression, and other psychiatric diagnoses (OR 2.1, 95% CI 1.1-3.9), the researchers reported online in the Journal of the American College of Cardiology.
Length of LAD Coronary Artery Determines Prognosis
Interesting study. The link takes you to the abstract.
Walk or Run? Think Distance, Not Speed
Researchers evaluated 33,060 runners in the National Runners’ Health Study and 15,045 walkers in the National Walkers’ Health Study. Dr. Thompson said there will be more results coming from the data. The study found:
- Running reduced the risk for first-time hypertension 4.2%, and walking reduced it by 7.2%.
- Running cut the risk for first-time high cholesterol 4.3%, and walking reduced it by 7.0%.
- Running cut the risk for first-time diabetes 12.1%, and walking decreased it by 12.3%.
- Running reduced coronary heart disease 4.5% compared with 9.3% for walking.
via Walk or run? Think distance, not speed, for health benefits – amednews.com.
GREAT NEWS for this aging tortoise who no longer runs 10-k’s due to bilateral knee osteoarthritis.
Researchers Suggest 2 Paths to get Patients Back on Statins
…statin discontinuation is common and has been linked to a greater risk of heart-related events and death in patients who have coronary artery disease, the study said.
via Researchers suggest 2 paths to get patients back on statins – amednews.com.
One out of every four Americans over the age of 45 are on a statin.
Coronary Calcium Score Predicts Cardiovascular Mortality in Diabetes
CONCLUSIONS: In T2DM, CAC predicts CVD mortality and meaningfully reclassifies participants, suggesting clinical utility as a risk stratification tool in a population already at increased CVD risk.
via Coronary Calcium Score Predicts Cardiovascular Mortality in Diabetes.
Whoa.
Association of Clinical Symptomatic Hypoglycemia With Cardiovascular Events and Total Mortality in Type 2 Diabetes
CONCLUSIONS: Symptomatic hypoglycemia, whether clinically mild or severe, is associated with an increased risk of cardiovascular events, all-cause hospitalization, and all-cause mortality. More attention may be needed for diabetic patients with hypoglycemic episodes.
Watch those hypoglycemic episodes in applicants with T2DM.
Red Meat’s Heart Risk Goes Beyond The Fat : NPR
Red Meat’s Heart Risk Goes Beyond The Fat : NPR.
Everything you need to know about L-carnitine and TMAO (Trimethylamine N-oxide).
Diastolic Dysfunction Common in RA
Patients with rheumatoid arthritis (RA) have an increased incidence of diastolic dysfunction, which may further raise their already high risk for congestive heart failure, a meta-analysis suggested.
Patients with RA have double the incidence of heart failure compared with the larger population, and this finding has prompted interest in determining the origins of heart failure in these patients.
lifeunderwriter.net 
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