RESULTS Incidence of diabetes during the follow-up was 17.1%. Two of three of the cases of newly diagnosed diabetes were predicted by a raise in ≥1 of the markers. Elevated A1C, IGT, or IFG preceded diabetes in 32.8, 40.6, and 21.9%, respectively. CVD was predicted by an intermediate and diabetic range of 2-h glucose but only by diabetic A1C levels in women.
CONCLUSIONS A1C predicted 10-year risk of type 2 diabetes at a range of A1C 5.7–6.4% but CVD only in women at A1C ≥6.5%.
Medical News: ADA: Mortality Lower with Metformin – in Meeting Coverage, ADA from MedPage Today
A large, multicenter trial found a 24% reduced risk of all-cause mortality among patients on the drug, compared with those not taking it, according to Ronan Roussel, MD, PhD, of Groupe Hospitalier Bichat-Claude Bernard in Paris, and colleagues.
Glycemic Control and Cardiovascular Disease in 7,454 Patients With Type 1 Diabetes — Diabetes Care
CONCLUSIONS This observational study of patients in modern everyday clinical practice demonstrates progressively increasing risks for CHD and CVD with higher A1C, independently of traditional risk factors, with no J-shaped risk curves. A baseline mean A1C of 7.2% showed considerably reduced risks of CHD and CVD compared with A1C 9.0%, emphasizing A1C as a strong independent risk factor in type 1 diabetes.
Glucose-Independent, Black–White Differences in Hemoglobin A1c Levels — Ann Intern Med
Remember, we do not use race in our underwriting.
Small study, interesting findings.
BBC News – Insulin giant pulls medicine from Greece over price cut
Before you formulate an opinion, make sure to read the last sentence in this article.
By way of compensation, he said the company would make available an insulin product called glucagen, free of charge.
I know people have been asking about drinking and being diabetic, and it’s a very honest question,” he blogged. “Here is the honest answer, and this is the truth: when I say ‘party’ and ‘let’s have fun,’ I’m one of those guys that just likes to have a great time. I’m not a belligerent drunk. I don’t need to drink. … For a diabetic … it’s a double whammy because here’s what happens with alcohol: when you’re hung-over then you don’t eat right, you don’t take your insulin right. So it’s best to stay away. But, I pick and choose my times when I’m going to have fun.
Reality star and aging rocker Bret Michaels, just weeks before his cerebral hemorrhage.
During 2004–2008, 7.6% of adults overall in the United States reported ever having been told they had diabetes. American Indian/Alaska Natives (17.5%), blacks (11.8%), and Hispanics (10.6%) were more likely than Asians (8.0%) and whites (6.6%) to report ever having been told by a doctor or health professional that they had diabetes.
More than 40% of people with undiagnosed diabetes had chronic kidney disease, based on albuminuria or reduced estimated glomerular filtration rate (eGFR) — just as many as in those with diagnosed diabetes, according to Laura C. Plantinga, ScM, of San Francisco General Hospital and University of California San Francisco, and colleagues.
Notably, 56.2% of chronic kidney disease was stage 3 or 4 among those with prediabetes, indicated by a fasting plasma glucose between 100 and 126 mg/dl, and for whom kidney dysfunction was likely unsuspected.
From April 2005 to October 2008, FDA received 78 reports of altered kidney function in patients treated with Byetta. Some of the patients had pre-existing kidney disease and other risk factors for developing kidney problems. Acute renal failure occurred in 62 patients and renal insufficiency in 16 patients.
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