Obesity is Not a Disease

David L. Katz, MD, MPH, FACPM, FACP, FACLM is a specialist in Internal Medicine, Preventive Medicine/Public Health, and Lifestyle Medicine – globally recognized for expertise in chronic disease prevention, health promotion, and nutrition. The founding director of Yale University’s Prevention Research Center, and past president of the American College of Lifestyle Medicine, Katz is the founder of the non-profit True Health Initiative, founder of Diet ID, and Chief Medical Officer for leading food-as-medicine company, Tangelo. He is a senior science advisor to Blue Zones. He holds multiple US patents, including for advances in dietary assessment. He has roughly 250 peer-reviewed publications, has authored 19 books- including multiple editions of a leading textbooks in nutrition and preventive medicine, and has earned numerous awards for his contributions to public health, including three honorary doctoral degrees.

https://www.vumedi.com/video/obesity-is-not-a-disease-so-what-is-it

Diet until proven otherwise.

Diet and Healthy Aging

In the journal Nature Medicine this week there was an important open-access publication about a large combined cohort of over 105,000 health professionals prospectively followed for 30 years. Only 9.3% reached the age of 70 years with “healthy aging” —without 11 major chronic diseases and no impairment of cognitive or physical function or mental health. Our Diet and Healthy Aging Eric Topol, MD – https://erictopol.substack.com/p/our-diet-and-healthy-aging

Dr. Eric Topol’s assessment of this study is well balanced and thoughtfully written. His bio is here: https://www.scripps.edu/faculty/topol/

Healthy aging in this study is described as reaching age 70 without developing any of 11 major diseases: cancer (except for non-melanoma skin cancers), diabetes, heart attack, coronary artery disease, congestive heart failure, stroke, kidney failure, chronic obstructive pulmonary disease, Parkinson disease, multiple sclerosis and amyotrophic lateral sclerosis.

My Half-Birthday is coming up soon. I’ll be 70.5 years young. The biggest take home lesson for me is this:

Beer is better for you than pizza.

Low Serum Levels of 3 Carotenoids Linked to Increased Risk for Migraine

The cross-sectional study, which was performed on a nationally representative United States cohort, indicated an inverse association between serum carotenoid levels and migraine risk in adults. https://www.clinicalpainadvisor.com/news/low-serum-levels-of-3-carotenoids-linked-to-increased-risk-for-migraine/

α-Carotene, β-Carotene, β-Cryptoxanthin, Lycopene, Lutein, and Zeaxanthin – https://lpi.oregonstate.edu/mic/dietary-factors/phytochemicals/carotenoids

Yum.

Smartphones, Ultra-Processed Foods, Diminished Family Bonds and Mental Wellness

As mental well-being has remained largely static across the world since 2021, so too have the rankings of countries. At the top of the rankings are many Latin American and African countries while much of the core Anglosphere ranks in the bottom quartile. With national wealth indicators such as per capita GDP negatively correlated with average mental well-being scores (see our 2021 report), this year we have made substantial progress in our understanding of why this is so. Two key findings published in Rapid Reports in 2023 show that younger age of first smartphone ownership and ultra-processed food consumption are two major contributors to our mental health challenges. In wealthier countries, the age of first smartphone ownership is much younger and ultra-processed food consumption much higher. Other contributing factors are the relatively diminished family relationships in wealthier countries that are highlighted in our 2022 annual report. The Mental State of the World in 2023https://mentalstateoftheworld.report/2023_read/

Another Sunday morning, just reading and connecting the dots.

I’ve downloaded several of these reports and plan to do a deep dive later.

Read these reports and think about it.

Now do something about it.

Prostate Cancer Diagnosis? Eat Less Omega-6 fats and More Omega-3 fats

To determine whether diet or supplements can play a role in managing prostate cancer, the UCLA-led team conducted a prospective clinical trial, called CAPFISH-3, that included 100 men with low risk or favorable intermediate risk prostate cancer who chose active surveillance. Participants were randomly assigned to either continue their normal diet or follow a low omega-6, high omega-3 diet, supplemented with fish oil, for one year.

The findings, published in the Journal of Clinical Oncology, show that a diet low in omega-6 and high in omega-3 fatty acids, combined with fish oil supplements, significantly reduced the growth rate of prostate cancer cells in men with early-stage disease.

University of California – Los Angeles Health Sciences. “A low omega-6, omega-3 rich diet and fish oil may slow prostate cancer growth.” ScienceDaily. http://www.sciencedaily.com/releases/2024/12/241213211326.htm (accessed December 13, 2024)

Another reminder I should get my PSA level checked.

Prostate Cancer Diagnosis? Eat More Veggies

In this cohort study of 2062 men with prostate cancer, higher intake of plant foods after prostate cancer diagnosis was associated with lower risk of cancer progression. These findings suggest nutritional assessment and counseling may be recommended to patients with prostate cancer to help establish healthy dietary practices and support well-being and overall health. Plant-Based Diets and Disease Progression in Men With Prostate Cancerhttps://jamanetwork.com/journals/jamanetworkopen/fullarticle/2818122

This reminds me I should get my PSA level checked at my next annual visit.

Last reading was 0.64 back in 2022.

Dietary Approaches to Obesity Treatment

There is no single diet that can universally fit everyone for weight loss benefit.

Parmar RM, Can AS. Dietary Approaches to Obesity Treatment. [Updated 2023 Mar 11]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2024 Jan-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK574576/https://www.ncbi.nlm.nih.gov/books/NBK574576/

Words of Wisdom from a former 370 pound human.

What worked for me may not work for you.

Keep searching for what works for you.

Find the differences that make a difference.

Good luck.

Diet and Your Immune System

Whereas nutrition scientists have conventionally studied the long-term impacts of loosely defined Mediterranean or Western diets, for example, today they have access to tools that allow them to zoom in on the short-term effects — both helpful and harmful — of narrower food groups and specific dietary components, and to probe the molecular mechanisms underpinning the effects of foods on immunity. Your diet can change your immune system — here’s how https://www.nature.com/articles/d41586-024-03334-0

Nice article summarizing the latest research in diet and the immune system.

Food for Thought (and memories)

Mealtime can provide opportunities to connect with someone experiencing memory loss and tap into deeply rooted memories. “If you’re going to make your father’s favorite meal, think about how you can delve into it as an experience,” Aguirre says. Dr. Kramer notes that several senses associated with cooking and eating dishes, including smell and taste, are closely related to memory. Both the olfactory bulb, the main receiving center for smell, and the insular cortex and frontal operculum (also called the gustatory cortex), responsible for perception of taste, are closely connected to the amygdala, an area involved in emotional learning. The olfactory nerve, which conveys the sense of smell to the brain, is also close to the hippocampus, one of the most important brain structures for memory. And the combined effect of smell and taste—what neuroscientists who study this field call “flavor”—can be especially powerful at conjuring long-held memories charged with emotion, says Joel Salinas, MD, MBA, FAAN, assistant professor of neurology at NYU Langone Health and chief medical officer at Isaac Health, a clinic in New York City for brain health and memory problems.Favorite Meals May Trigger Memories in People with Dementiahttps://www.brainandlife.org/articles/food-may-trigger-memories-in-people-with-dementia

Yogurt and CSBMs (Complete Spontaneous Bowel Movements)

In a randomized controlled trial, the probiotic Bifidobacterium animalis subsp. lactis—used in many probiotic products, including Dannon’s Activia yogurts—did nothing to improve bowel health in people with constipation, according to data from a randomized triple-blind placebo-controlled clinical trial published Wednesday in JAMA Network Open. Popular gut probiotic completely craps out in randomized controlled trialhttps://arstechnica.com/health/2024/10/popular-gut-probiotic-completely-craps-out-in-randomized-controlled-trial/

Here’s a lesson in the need to read the original study. I found this statement from the researchers:

The 2 study groups were very similar with respect to baseline characteristics. The participants had a low dietary fiber intake (9 g/d), which is in line with observations by others (11.7 g/d) and well below recommended levels (25.0 g/d).14 This may be a contributing factor to the bowel movement problems experienced by the participants. Eight-Week Supplementation With Bifidobacterium lactis HN019 and Functional Constipationhttps://jamanetwork.com/journals/jamanetworkopen/fullarticle/2824333

IMO the low dietary fiber intake in this shitting study leads me to think the entire study results were…crappy.

BTW yesterday I had two CSBMs. That’s what I get for eating a bowl of black eye peas http://garyskitchen.net/2022/01/16/vegetarian-badass-black-eyed-peas-2022/ and a baked sweet potato in the same day.