Emergency Medicine News – THC Dosing of Edible Marijuana in Colorado is Insane.

Avoid couchlock! Four things to know about cannabis pharmacology | The Poison Review.

Recently, the New York Times’ Pulitzer Prize-winning columnist Maureen Dowd got into trouble in Denver when she overdosed on a cannabis candy bar and experienced 8 hours of paranoia and couchlock.

Toxicology Rounds: Four Things Maureen Dowd Should Have Know… : Emergency Medicine News.

THC dosing of edible marijuana in Colorado is insane. Richard Zane, MD, the chairman of emergency medicine at the University of Colorado Medical Center in Denver, said on the National Public Radio talk show On Point that the amount of THC in some marijuana edibles is completely irrational. The usual recommended moderate starting dose is approximately 10 mg THC, and some cookies can contain six doses and some lollipops as many as 10. Dr. Zane said the university’s ED sees out-of-state marijuana tourists every day who present with bad reactions to THC, such as agitation, unremitting violent vomiting, hallucinations, and psychosis.

And finally, a link to Maureen Dowd’s column.

Don’t Harsh Our Mellow, Dude – NYTimes.com.

In March, a 19-year-old Wyoming college student jumped off a Denver hotel balcony after eating a pot cookie with 65 milligrams of THC. In April, a Denver man ate pot-infused Karma Kandy and began talking like it was the end of the world, scaring his wife and three kids. Then he retrieved a handgun from a safe and killed his wife while she was on the phone with an emergency dispatcher.

Diet Soda May Alter Our Gut Microbes And Raise The Risk Of Diabetes : The Salt : NPR

Now, a new study published in the journal Nature introduces a new idea: Diet sodas may alter our gut microbes in a way that increases the risk of metabolic diseases such as Type 2 diabetes — at least in some of us.

In the paper, researchers at the Weizmann Institute of Science in Israel describe what happened when they fed zero-calorie sweeteners, including saccharin, aspartame and sucralose, to mice.

“To our surprise, [the mice] developed glucose intolerance,” Weizmann researcher Eran Elinav tells us.

Artificial sweeteners induce glucose intolerance by altering the gut microbiota : Nature : Nature Publishing Group.

Diet Soda May Alter Our Gut Microbes And Raise The Risk Of Diabetes : The Salt : NPR.

Regular Fish Consumption and Age-Related Brain Gray Matter Loss – American Journal of Preventive Medicine

Regular Fish Consumption and Age-Related Brain Gray Matter Loss – American Journal of Preventive Medicine.

Conclusions

Dietary consumption of baked or broiled fish is related to larger gray matter volumes independent of omega-3 fatty acid content. These findings suggest that a confluence of lifestyle factors influence brain health, adding to the growing body of evidence that prevention strategies for late-life brain health need to begin decades earlier.

Frozen fish sticks were a staple in my childhood diet.

I hope it helped.

Fruit, Veg Intake Has Dose-Response Link With CV Death

The inverse association between increased fruit and vegetable consumption and mortality was particularly noticeable for cardiovascular mortality; higher consumption was not significantly linked with reduced risk of cancer mortality

All of the pitfalls of the component studies are present in the meta-analysis, the authors warn, including the fact that fruit and vegetable intake is typically self-reported. Not all studies adjusted for other types of foods consumed, including saturated fats, processed meats, etc. The definition of “portions” may also have been different across studies, the authors caution.

via Fruit, Veg Intake Has Dose-Response Link With CV Death.

Vegans and radical vegetarians take note.  Bold in quote above is my emphasis.

 

Stupidity is Worse for us than Either Sugar or Saturated Fat

Stupidity is worse for us than either sugar or saturated fat.

Read this article and you’ll encounter a well reasoned rant with lots of links for further reading enjoyment.  My personal journey includes a significant weight loss experience in my early 20’s.  Over the years I’ve gained back some of the 200 plus pounds lost.  Over the years I’ve also gotten lazy with my dietary habits.  Too many calories and an aging metabolism is not a combination for staying trim.  So I got serious (again) and have dropped 12 pounds the past three months.  I’ve always known what to do but failed to do what needed to be done.

And so it goes.  Change. Adapt. Repeat.