In the general linear model adjusted for age, sex, comorbidities, and BMI, serum 25(OH)D concentrations were significantly lower among COVID-19 patients than the 2018–2019 controls [ln transformed values of 3.32 ± 0.04 vs. 3.46 ± 0.022 ln (nmol/L), P = 0.014]. Multivariable logistic regression showed that male sex (OR: 2.26; 95% CI: 1.06, 4.82), advanced age (≥65 y) (OR: 4.93; 95% CI: 1.44, 16.9), and vitamin D deficiency (<30 nmol/L) (OR: 2.72; 95% CI: 1.23, 6.01) were significantly associated with COVID-19 severity (all P < 0.05).
These findings suggested that vitamin D deficiency impacts COVID-19 hospitalization and severity in the Chinese population.Vitamin D Deficiency Is Inversely Associated with COVID-19 Incidence and Disease Severity in Chinese People — The Journal of Nutrition, Volume 151, Issue 1, January 2021, Pages 98–103, https://doi.org/10.1093/jn/nxaa332
More links are in my last post Vitamin D – What’s Your Level?
I am hoping all of my Chinese relatives read this.
The multi-center study included 957 people in South Korea with benign paroxysmal positional vertigo who had undergone canalith repositioning maneuvers—head movements that shift displaced calcium carbonate crystals in the inner ear. The intervention group included patients who received 400 IU vitamin D and 500 mg calcium carbonate twice daily for 1 year when their baseline serum vitamin D level was below 20 ng/mL along with patients who had higher baseline levels and took no supplements. An observation group had no baseline testing or interventions.
The supplements significantly reduced the annual vertigo recurrence rate by 24%. There were 0.83 recurrences per 1 person-year in the intervention group compared with 1.10 in the observation group. Patients with greater vitamin D deficiencies at baseline derived the most benefit.JAMA. 2020;324(16):1599. doi:10.1001/jama.2020.18695 — https://jamanetwork.com/journals/jama/fullarticle/2772275
BPPV = benign paroxysmal positional vertigo. The original study in Neurology and the JAMA summary both use the word “prevent” in their respective titles. I think reduce is a more apt description. Semantics aside a 24% reduction in recurrent BPPV episodes is significant.
And yet another example of nutritional deficiencies underlying another disease.
Vitamin B12 (known as cobalamin) is an essential dietary component but vegetarians are more prone to B12 deficiency as plants neither make nor require this nutrient.
But now a team, led by Professor Martin Warren at the University’s School of Biosciences, has proved that common garden cress can indeed take up cobalamin.
The amount of B12 absorbed by garden cress is dependent on the amount present in the growth medium, and the Kent team was able to confirm B12 uptake by showing that the nutrient ends up in the leaf.
I can’t wait for the silly money and marketers to grab this and run.
Read the source article here.
USPharmacist.com > Vitamin Deficiencies in Seniors.
Follow this link for some nice charts on nutritional deficiencies in seniors. Read the article and I promise you will never read an APS the same way ever again.