Blood Glucose on Admission Predicts COVID-19 Severity

The retrospective, multicenter study was based on data from 11,312 adult patients with confirmed COVID-19 in 109 hospitals participating in Spain’s SEMI-COVID-19 registry as of May 29, 2020. They had a mean age of 67 years, 57% were male, and 19% had a diagnosis of diabetes. A total of 20% (n = 2289) died during hospitalization.

Overall all-cause mortality was 41.1% among those with admission blood glucose levels above 180 mg/dL, 33.0% for those with glucose levels 140-180 mg/dL, and 15.7% for levels below 140 mg/dL. All differences were significant (P < .0001), but there were no differences in mortality rates within each blood glucose category between patients with or without a previous diagnosis of diabetes.

After adjustment for confounding factors, elevated admission blood glucose level remained a significant predictor of death. Compared to < 140 mg/dL, the hazard ratios for 140-180 mg/dL and > 180 mg/dL were 1.48 and 1.50, respectively (both P < .001). (Adjustments included age, gender, hypertension, diabetes, chronic obstructive pulmonary disease, lymphopenia, anemia (hemoglobin < 10 g/dL), serum creatinine, C-reactive protein > 60 mg/L, lactate dehydrogenase > 400 U/L and D-dimer >1000 ng/mL.)

Cite this: Blood Glucose on Admission Predicts COVID-19 Severity in All – Medscape – Nov 30, 2020. — https://www.medscape.com/viewarticle/941716?src=rss#vp_2

Journal abstract link – https://www.tandfonline.com/doi/abs/10.1080/07853890.2020.1836566

8 thoughts on “Blood Glucose on Admission Predicts COVID-19 Severity

  1. Interesting.

    I just got home after being sprayed with millions of droplets. I had just gotten in my car, and a guy I know who works at the community center wanted to ask me a medical question, so I was outdoors, but sitting in my car with the door open and as he was talking. I could tell he was one of those spitters. I could see all the droplets floating toward me. I wish I had had the presence of mined to grab my mask which was on the seat next to me. But probably by that time the mask was covered in droplets.

    I just took a zinc pill. Hoping for the best.

    • You’re probably fine. Outdoors, short duration (despite the “millions” of droplets. If you want better peace of mind I’d find out if anyone who works at the community center has been infected with SARS COV-2. But I’m neither a public health expert or physician. We kept our Thanksgiving very small. I feel my risk was higher visiting the kid who deals with Covid on every shift than your chance encounter.

      • That’s what I’m hoping as well. I’ll have to ask at the community center. I know them well. Somebody there had Covid last summer. But I don’t know anything about infections recently. They are not open to the public, so it is just minimally staffed. The guy who was talking to me is the custodian there. He’s a very nice guy, I have known him for years. I know he’s not been sick recently, since he’s been working every day I do Tai Chi for the past several months. He had a heart attack last spring. So I know he is at risk. But the medical problem he was asking about was his foot, plantar fasciitis. Not anything respiratory.

  2. Yes, your Thanksgiving was probably higher risk than my brief encounter. But I’m assuming your kid gets tested frequently and as an emergency physician is taking all the precautions. I hope you had a good Thanksgiving! Mine was by myself this year just the golden retriever and me. And I turned 70!

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