First It Was Masks; Now Some Refuse Testing for SARS-CoV-2

Test avoidance appears to be a growing problem, at least anecdotally. Many of the same people who dismiss the need to test feel the same way about wearing a mask, in part because they think no one has the right to tell them to do either.

First It Was Masks; Now Some Refuse Testing for SARS-CoV-2 – JAMA. 2020;324(20):2015-2016. doi:10.1001/jama.2020.22003 – https://jamanetwork.com/journals/jama/fullarticle/2772860

I am speechless.

Taking a Road Trip? Here’s Your Checklist

This article has not been edited and the article was originally published on The Conversation. https://theconversation.com/planning-a-road-trip-in-a-pandemic-11-tips-for-before-you-leave-on-the-road-and-when-you-arrive-149620

Planning a road trip in a pandemic? 11 tips for before you leave, on the road and when you arrive
November 26, 2020

Author – Thea van de Mortel
Professor, Nursing and Deputy Head (Learning & Teaching), School of Nursing and Midwifery, Griffith University

As restrictions ease around the country and the prospect of travel beckons, many of us will be planning road trips for the holiday season.

To ensure your trip is memorable in the best rather than the worst way, here are some things you and your fellow travellers can do to reduce the risk of becoming infected with, or spreading, COVID on your trip.

Before you go

  1. Check for any travel or other COVID-specific restrictions or rules in the areas you will be travelling through or to, before you go. These can change rapidly and may include restrictions on how far you can travel, how many people per square metre are allowed in public spaces, and whether you need border passes or to wear a mask. Each state or territory has its own health department or government COVID website you can check.
  2. Don’t take COVID with you. If anyone in your group has COVID-like symptoms, however mild, it is important to be tested and cleared for COVID before leaving. Common symptoms may include fever or chills, muscle aches, sore throat, cough, runny nose, difficulty breathing, new loss of taste or smell, and vomiting or diarrhoea.
  3. Pack masks, disinfectant wipes and hand sanitiser. The two most likely ways of catching COVID are inhaling viral particles an infected person sheds when they cough, sneeze, laugh, talk or breathe; and ingesting particles by touching contaminated objects and then touching your face or food. Masks (and social distancing) can help reduce the former risk, while avoiding touching your face, frequent hand hygiene and cleaning surfaces can reduce the latter. So pack masks, wipes and hand sanitiser. Hand sanitiser should contain at least 60% alcohol.
  4. Pack your own pillows and linen. We know people infected with SARS-CoV-2, the virus that causes COVID, can shed virus onto linen and pillows (and other surfaces), even when asymptomatic. We also know respiratory viruses can penetrate pillow covers and get into the microfibre stuffing. So you might want to consider bringing your own pillows and linen.

On your trip

  1. Use disinfectant wipes to clean high-touch surfaces in your hire car. These would include door and window handles or buttons, light switches, seat adjuster controls, radio controls, the steering wheel, glove box button, gear/drive and handbrake levers, rear-view mirrors and mirror controls.
  2. How about singing in the car? The more vigorous the activity, the greater the opportunity to release droplets and aerosols and the further these will travel. So, laughing and singing will release more of these than talking, and talking will release more than breathing. However, if you are travelling in a family group, or with your housemates, then you have been in close contact with one another at home and the additional risk would be low.
  3. Maintain social distancing at service stations. Leave at least 1.5 metres between you and the next person while paying for fuel, ordering food and when using the bathroom. Make sure you wash or sanitise your hands after touching surfaces such as petrol pumps, door handles, bathroom taps, and before getting back in your car.
    Filling car up with petrol at service station
    Wash or sanitise your hands after using the petrol pump. Shutterstock
  4. Pay with cards rather than cash to avoid touching money. Many people can handle bills and coins over a long duration of time, providing many opportunities to transfer disease-causing microbes from one person to the next. Using contactless payment also helps maintain social distancing.
  5. It’s safer to eat outdoors than indoors if stopping for a snack or lunch. That’s because large volumes of air dilute the density of viral particles in the air. Evidence from a study of COVID clusters in Japan suggests the chance of transmitting COVID is more than 18 times higher inside than outside.

When you arrive

  1. Is your hotel or rented accommodation COVID-safe? Ask the accommodation provider what steps they have taken to make the place less conducive to spreading COVID. For example, have they introduced extra cleaning or disinfection?
  2. Use disinfectant wipes in rented accommodation to clean high-touch surfaces such as door handles, light switches, cupboard handles, taps and toilet flush buttons. You can also put dishes and cutlery through the dishwasher on a hot cycle. This is because the virus can remain viable (able to cause infection) on surfaces for many days.

Following these simple steps can help to keep your trip memorable in the best possible way. Happy holidays!

Copyright © 2010–2020, The Conversation US, Inc.

Personality Traits Linked to Toilet Paper Stockpiling

The most robust predictor of toilet paper stockpiling was the perceived threat posed by the pandemic; people who felt more threatened tended to stockpile more toilet paper. Around 20 percent of this effect was also based on the personality factor of emotionality — people who generally tend to worry a lot and feel anxious are most likely to feel threatened and stockpile toilet paper. The personality domain of conscientiousness — which includes traits of organization, diligence, perfectionism and prudence — was also a predictor of stockpiling.

Max Planck Institute for Evolutionary Anthropology. “Personality traits linked to toilet paper stockpiling: High levels of emotionality and conscientiousness are indicators for stockpiling behavior.” ScienceDaily. http://www.sciencedaily.com/releases/2020/06/200612172227.htm (accessed November 25, 2020).

In case you haven’t noticed it’s happening again. Where’s the toilet paper?

More on Vulvar Melanoma

Lesions could be angiokeratomas, petechiae, purpura, melanosis, and nevi, for example. Seborrheic keratoses can mimic melanoma. “If it looks odd, don’t be afraid to biopsy it,” said Mauskar, assistant professor of dermatology and obstetrics and gynecology at the University of Texas Southwestern Medical Center in Dallas.

Low Threshold to Biopsy Atypical Lesions May ID Vulvar Melanoma Early, Experts Say — https://www.medscape.com/viewarticle/941157?src=rss

I first became aware of melanoma down there back in June of this year. See Vulvar Melanoma Is Increasing in Older Women

So remember, if it looks odd get it biopsied.

COVID-19: Study Suggests Durable Immune Response After SARS-CoV-2 Infection

Immune responses to SARS-CoV-2 might last for years, according to a study posted on the preprint server bioRxiv.

Some 185 adults who recovered from COVID-19 (most had mildly symptomatic disease) provided blood samples for analysis. The majority provided a single sample, but roughly 20% provided multiple samples over several months.

The researchers found that levels of spike-specific memory B cells (which make antibodies as needed) increased with time — and were higher at 4–6 months than at earlier time points in most participants who gave multiple samples. In addition, SARS-CoV-2 spike IgG titers were generally stable, showing only modest declines at 6–8 months.

COVID-19: Study Suggests Durable Immune Response After SARS-CoV-2 Infection — https://www.jwatch.org/fw117245/2020/11/17/covid-19-study-suggests-durable-immune-response-after

I hope these findings are replicated in other studies.

Meanwhile in Oklahoma – About That Mask Debate 11.13.20

Oklahoma Weekly Epidemiology and Surveillance Report 11/6-11/12 2020

In Oklahoma we don’t have a statewide mask mandate. Mask mandate decisions are at the city level. The last time I looked at these numbers I focused on the percent change from 8/1 to the present study date. Today my eyes focused on the Nov. 1 seven day average case numbers mask vs no mask. My small brain is trying to understand what I’m seeing. Under the assumption mask wearing is effective in helping stop the virus from spreading why is the gap narrowing?

Numbers notwithstanding, I’m still going to wear a mask.

Hydroxychloroquine does NOT counter SARS-CoV-2 in Hamsters, High Dose of Favipiravir DOES

GREAT NEWS for hamsters!

A high dose of favipiravir, however, had a potent effect. A few days after the infection, the virologists detected hardly any infectious virus particles in the hamsters that received this dose and that had been infected intranasally. Moreover, hamsters that were in a cage with an infected hamster and had been given the drug did not develop an obvious infection. Those that had not received the drug all became infected after having shared a cage with an infected hamster.

KU Leuven. “Hydroxychloroquine does not counter SARS-CoV-2 in hamsters, high dose of favipiravir does: study.” ScienceDaily. ScienceDaily, 9 October 2020. www.sciencedaily.com/releases/2020/10/201009162432.htm.

Hopefully good news for humans.

Favipiravir: A new and emerging antiviral option in COVID-19

Favipiravir was first used against SARS-CoV-2 in Wuhan at the very epicenter of the pandemic. Then, as the pandemic spread to Europe, this drug received approval for emergency use in Italy, and currently has been in use in Japan, Russia, Ukraine, Uzbekistan, Moldova, and Kazakhstan. Approval has also recently been granted in Saudi Arabia and the UAE. Thereafter, Turkey, Bangladesh, and most recently Egypt have also seen recent commercial launches. In June 2020, favipiravir received the DCGI approval in India for mild and moderate COVID-19 infections. As of the 23rd of July, 2020; there are 32 studies registered on clinicaltrials.gov to assess the utility of this drug in the management of COVID-19 (3 completed, 12 recruiting).1

Favipiravir: A new and emerging antiviral option in COVID-19 — http://Med J Armed Forces India. 2020 Sep 2 doi: 10.1016/j.mjafi.2020.08.004 [Epub ahead of print]

Yale study reveals which gender is better at social distancing. Take a guess

Researchers headed to the streets in New York City; New Haven, Connecticut; and New Brunswick, New Jersey, and tracked the behaviors of unsuspecting passersby. They also analyzed the movements of 15 million cellphone GPS data points, and surveyed 800 people about their practices. They found that women are far superior at wearing masks, social distancing, and hand washing, and are more likely to stay home and limit contact with family and friends. Women also are more likely to rely on advice from medical experts.

Yale study reveals which gender is better at social distancing. Take a guesshttps://www.fastcompany.com/90562466/yale-study-reveals-which-gender-is-better-at-social-distancing-take-a-guess?partner=rss&utm_source=feedburner&utm_medium=feed&utm_campaign=feedburner+fastcompany&utm_content=feedburner