American Institute for Cancer Research (AICR): CRU: Report: Obesity and 3 Daily Alcoholic Drinks Increase Liver Cancer Risk

The report also reaffirms the clear link between alcohol consumption and liver cancer, and for the first time quantifies the amount at which risk for liver cancer rises. “We now have a little more precision on the alcohol-liver cancer link,” said Hursting. “Getting above three drinks a day seems to dramatically impact the tumorigenic process and increase risk.”

via American Institute for Cancer Research (AICR): CRU: Report: Obesity and 3 Daily Alcoholic Drinks Increase Liver Cancer Risk.

More coffee!  Less beer!


OncoBriefs: Hookah Risk

OncoBriefs: Hookah Risk, Brain Cancer, Lung Cancer.

Urinary concentration of the benzene metabolite S-phenylmercapturic acid (SPMA) was more than four times greater in hookah smokers and two times greater in people exposed to secondhand hookah smoke, when compared with people who had no exposure. The findings put a damper on enthusiasm for hookah as a safer alternative to cigarettes, as reported online in Cancer Epidemiology, Biomarkers and Prevention.

Sleep Apnea Linked to Cancer

Sleep Apnea Linked to Cancer.

Moderate-to-severe OSA was associated with a 2.5-fold higher likelihood of incident cancer (95% CI 1.2-5.0) after adjustment for obesity and a full range of other factors, Nathaniel Marshall, PhD, of the University of Sydney Nursing School in Australia, and colleagues found.

Cancer mortality was 3.4 times more common (95% CI 1.1-10.2) in those with sleep apnea than with no sleep apnea during 20 years of follow-up, they reported in the April 15 issue of theJournal of Clinical Sleep Medicine.

Pancreatitis May Confer Higher Risk for Cancer

In an effort to quantify the relationship between acute pancreatitis and pancreatic cancer, Agarwal and colleagues reviewed inpatient and outpatient records for 495,504 patients who received care through the Veterans Health Administration from 2000 through 2007. The authors identified 5,720 patients who had one or more episodes of acute pancreatitis, 710 of whom subsequently had diagnoses of pancreatic cancer.

Median follow-up was 60 months for the entire cohort, 26 months for patients who developed pancreatic cancer, and 60 months for patients who did not develop pancreatic cancer.

The patient cohort was predominately male (89%). A third of the patients smoked, a fourth had a history of heavy alcohol use, and 3% had a history of gallstones.

The 710 patients included 86 who had one or more episodes of acute pancreatitis prior to cancer diagnosis. The authors found that 76 of the 86 patients had a least one episode of acute pancreatitis within 2 years of cancer diagnosis.

In 69 of the 76 cases, the preceding pancreatitis occurred within a year of pancreatic cancer diagnosis. In fewer than half of the cases (N=34), acute pancreatitis preceded pancreatic cancer diagnosis by 2 months or less.

via Pancreatitis May Confer Higher Risk for Cancer.