Russia’s coronavirus vaccine elicits immune responses in Phase-1/2 trials — Science Chronicle

Russia’s Sputnik V vaccines for novel coronavirus have been found to be safe for a period of 42 days and capable of inducing antibody responses in all the 42 participants within 21 days. But the Phase-1/2 trials were open, not randomised, did not have a control group, and included totally 76 participants.

According to the authors, the unpublished data of animal studies show “robust humoral and cellular immune responses were elicited in non-human primates, providing protection from SARS-CoV-2 infection”. They also write that the vaccine showed “100% protectivity in a lethal model of SARS-CoV-2 challenge in immunosuppressed hamsters”. No antibody-dependent enhancement of infection was seen in vaccinated animals.

Russia’s coronavirus vaccine is safe, elicits immune responses in Phase-1/2 trials — Science Chronicle

Safe? 76 humans and an undisclosed number of hamsters.

Why am I not impressed?

One thought on “Russia’s coronavirus vaccine elicits immune responses in Phase-1/2 trials — Science Chronicle

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