Covid-19 Vaccines and Myocarditis: Balancing Benefits and Risks in Adolescents and Young Adults — The Skeptical Cardiologist

Two days ago the FDA indicated it will add a warning about rare cases of myocarditis in adolescents and young adults to information sheets for the Pfizer/BioNTech, and Moderna COVID-19 vaccines. This followed a decision made by CDC advisor that myocarditis in adolescents and young adults is likely linked to the vaccines, but that the benefits…

Covid-19 Vaccines and Myocarditis: Balancing Benefits and Risks in Adolescents and Young Adults — The Skeptical Cardiologist

Thank you Dr. Pearson.

Full vaccination with AstraZeneca offers 92% protection against hospitalisation with delta variant — Science Chronicle

With the delta variant, both AstraZeneca and Pfizer vaccines offer high protection against hospitalisation. One dose of AstraZeneca vaccine offered 71% protection against hospitalisation, while two doses offered 92% protection. In the case of Pfizer vaccine, the protection against hospitalisation was 94% after one dose and 96% after two doses. A real-world study undertaken by […]

Full vaccination with AstraZeneca offers 92% protection against hospitalisation with delta variant — Science Chronicle

The study referenced is a pre-print and has not been peer reviewed.

The Saddest Covid-19 Statistic

“For those of us in public health, it’s nothing short of amazing,” Dr. Jeff Duchin, the chief health officer for Seattle and King County, told me the other day. I had called Duchin to ask about a startling claim he made recently. At a weekly health briefing, he offhandedly remarked that of King County’s recent COVID-19 cases, 97% had occurred in unvaccinated people. It effectively meant the only people still catching coronavirus here in King County are people who haven’t gotten the shots. It also means the disease that just a few months ago threatened the entire nation is now almost exclusively circulating among a shrinking few.

“We’re getting to the point where it’s a tale of two societies,” says Dr. Umair Shah, the state health secretary.Shah reported this past week that unvaccinated people between ages 45 and 64 are now being hospitalized for COVID at rates 21 times higher than the vaccinated.

The ‘two societies’: 97% of new COVID cases are among people who haven’t gotten the shots — https://www.seattletimes.com/seattle-news/health/the-two-societies-97-of-new-covid-cases-are-among-people-who-havent-gotten-the-shots/#comments

At the Seattle Times website for this article you’ll find over 500 comments. After reading several comments I had to stop. Every comment I read made me sad about all of the things we have gotten wrong during the pandemic. One of the worst things that has happened was the politicization of Covid-19. Sometimes I just wish it would stop.

If for whatever reason you choose to refuse the vaccine I have no interest in debating your decision. I’ll present some facts and we can remain cordial.

My Only Other Comment on Covid-19 Vaccine Blood Clot Risk

My only comment on the J&J vaccine blood clot risk was a technically correct statement. This is my only other comment on Covid-19 Vaccine induced blood clot risk. Get vaccinated. We now know how to fix it.

“Our experience shows us that these clot reactions are very rare, but they can be treated,” lead co-author Dr. R. Todd Clark, an assistant professor of emergency medicine at the University of Colorado School of Medicine, said in a statement. “Americans can feel comfortable getting vaccinated and should discuss any vaccination concerns with their doctor.”

Doctors successfully treat rare J&J blood clot, case report shows — https://www.livescience.com/johnson-and-johnson-vaccine-blood-clot-treatment-case-report.html

“COVID-19 infection is a significant risk factor for CVST. A preliminary analysis of U.S. data during the COVID-19 pandemic, available online, preprint on April 15, 2021, found that the risk of CVST due to infection with COVID-19 is 8-10 times higher than the risk of CVST after receiving a COVID-19 vaccine. The public can be reassured by the CDC’s and FDA’s investigation and these statistics – the likelihood of developing CVST after a COVID-19 vaccine is extremely low. We urge all adults to receive any of the approved COVID-19 vaccines.”

Karen L. Furie, M.D., M.P.H., lead author of the special report, chair of the department of neurology at The Warren Alpert Medical School of Brown University, and chief of neurology at Rhode Island Hospital, The Miriam Hospital and Bradley Hospital in Providence, Rhode Island

Guidance on diagnosis and management of cerebral venous sinus thrombosis after a COVID-19 vaccine — https://www.news-medical.net/news/20210429/Guidance-on-diagnosis-and-management-of-cerebral-venous-sinus-thrombosis-after-a-COVID-19-vaccine.aspx

Like I said earlier, I have a lot of respect for Brownies.

The Latest in COVID-19 News: Week Ending 04.24.21 – NEJM Journal Watch

Click on the link for the NEJM Journal Watch weekly update.  Not a lot of links this week for SARS-CoV-2 articles but again I did not forget to post this.

https://www.jwatch.org/fw117733/2021/04/24/covid-19-news-week-ending-apr-24-2021

So in the spirit of big news that didn’t get mentioned in this week’s NEJM Journal Watch:

FDA, CDC Lift Suspension of Johnson & Johnson Vaccine

Cite this: FDA, CDC Lift Suspension of Johnson & Johnson Vaccine – Medscape – Apr 23, 2021 — https://www.medscape.com/viewarticle/949913

Meanwhile pray for India.

India has recorded nearly a million infections in three days, with 346,786 new cases overnight into Saturday.

India Covid surge: Hospitals send SOS as record deaths registered — https://www.bbc.com/news/world-asia-56870410

My Only Comment on the J&J Covid Vaccine Blood Clot Risk

Dr. Karb was in the same residency class at Brown as Dr. Lee.

I have much respect for Brownies.

That’s it. My only comment on the J&J vaccine blood clot risk.

Just Another SARS-CoV-2 Vaccine Chart – Updated 03.25.21

Vaccine table produced by Monica Gandhi MD MPH. Downloaded from Twitter 03.27.21

Monica Gandhi MD, MPH is Professor of Medicine and Associate Division Chief (Clinical Operations/ Education) of the Division of HIV, Infectious Diseases, and Global Medicine at UCSF/ San Francisco General Hospital. She also serves as the Director of the UCSF Center for AIDS Research (CFAR) and the Medical director of the HIV Clinic at SFGH (“Ward 86”). Dr. Gandhi completed her M.D. at Harvard Medical School and then came to UCSF in 1996 for residency training in Internal Medicine. After her residency, Dr. Gandhi completed a fellowship in Infectious Diseases and a postdoctoral fellowship at the Center for AIDS Prevention Studies, both at UCSF. She also obtained a Masters in Public Health from Berkeley in 2001 with a focus on Epidemiology and Biostatistics.

https://profiles.ucsf.edu/monica.gandhi

SARS-CoV-2 mRNA vaccines induce a robust germinal centre reaction in humans

That lump in your armpit may actually be a good thing. The study is a pre-print with a small number of study subjects.