Source: Cardiac effects of loperamide overdose | The Poison Review
Just when you start to think you’ve heard it all you stumble upon this article. I’ve never thought about taking mass quantities of anti-diarrheal medication for the purpose of getting high.
A little-known manifestation of loperamide toxicity is cardiac dysrhythmias. This case report describes a 48-year-old woman who had ingested up to 40 tablets 2-mg loperamide daily for several weeks to “get a high.”
But CVD, colon cancer recommendation still has very thin evidence, experts caution
Source: CardioBrief: USPSTF Backs Aspirin for Primary Prevention | Medpage Today
Still taking daily aspirin? Stopped? Confused?
Join the club. I’ve been following this issue for years. Read more here, here, and and here.
Conclusions: Treatment with rosuvastatin at a dose of 10 mg per day resulted in a significantly lower risk of cardiovascular events than placebo in an intermediate-risk, ethnically diverse population without cardiovascular disease. (Funded by the Canadian Institutes of Health Research and AstraZeneca; HOPE-3 ClinicalTrials.gov number, NCT00468923.)
Source: Cholesterol Lowering in Intermediate-Risk Persons without Cardiovascular Disease — NEJM
Source: Blood-Pressure Lowering in Intermediate-Risk Persons without Cardiovascular Disease — NEJM
Source: Blood-Pressure and Cholesterol Lowering in Persons without Cardiovascular Disease — NEJM
Source: CNS – Pfizer to Face Testosterone Claims After All
The multi-district master complaint asserted 10 primary state law claims, including strict liability based on design defect and failure to warn, negligence, breach of implied and express warranty, fraud, consumer protection, and unjust enrichment.
The plaintiffs also allege non-tort claims for wrongful death, survival, loss of consortium, and punitive damages.
One of the books I’m reading is Powerful Medicines – The Benefits, Risks, and Costs of Prescription Drugs written by Jerry Avorn M.D. Definitely a fun read in the context of our culture’s addiction to the quick fix. Whatever ails you there is a pill that promises to fix everything. Dr. Avorn’s book is packed with information. Simply stated, there are benefits and risks associated with any medication. Ultimately it is the consumer’s responsibility to know and understand what those benefits and risks are with anything you put in your body.
It was clear to me from the beginning that the unsuspecting and too trustful public was going to be introduced to a new disease Low-T. The pharmaceutical strategy was just another medicalization of a natural process.
More. Drugs. Please.
Incidence of side effect is probably underestimated
Source: RheumNow: Drugs That May Induce Raynaud’s | Medpage Today
Meldonium is also known as mildronate, it increases exercise capacity in athletes and the Olympic figure skater Ekaterina Bobrova admitted to testing positive to the drug on Monday
Source: What is meldonium and why did Maria Sharapova use it? | Sport | The Guardian
About a third of patients noncompliant; some take other illicit drugs instead
Source: Urine Screens Show Patients Don’t Take ADHD Meds | Medpage Today
In a prospective, community-based study involving more than 10,000 adults followed for a median of 14 years, baseline use of a proton pump inhibitor (PPI) was independently associated with a 20% to 50% higher risk for incident chronic kidney disease (CKD).
Source: PPIs Tied to Increased Risk for Chronic Kidney Disease | Medpage Today
I got heartburn reading this article.
lifeunderwriter.net 
You must be logged in to post a comment.