Statin or Supplements?

So, which is most effective? Researchers at the Cleveland Clinic set out to answer this question by comparing statins to supplements in a clinical trial. They tracked the outcomes of 190 adults, ages 40 to 75. Some participants were given a 5 mg daily dose of rosuvastatin, a statin that is sold under the brand name Crestor for 28 days. Others were given supplements, including fish oil, cinnamon, garlic, turmeric, plant sterols or red yeast rice for the same period.

“What we found was that rosuvastatin lowered LDL cholesterol by almost 38% and that was vastly superior to placebo and any of the six supplements studied in the trial,” study author Luke Laffin, M.D. of the Cleveland Clinic’s Heart, Vascular & Thoracic Institute told NPR. He says this level of reduction is enough to lower the risk of heart attacks and strokes. The findings are published in the Journal of the American College of Cardiology.

Statins vs. supplements: New study finds one is ‘vastly superior’ to cut cholesterol – https://www.npr.org/sections/health-shots/2022/11/06/1134094540/statins-vs-supplements-new-study-finds-one-is-vastly-superior-to-cut-cholesterol

Sometimes diet and exercise alone are not enough to keep cholesterol in check. I currently take a low dose statin 10 mg daily. My test results from 09.27.22: cholesterol 197, HDL 71, LDL 102, triglycerides 69.

Oh, and continuing the theme of full disclosure the thing on my leg Image Challenge – November 2022 was MUD.

What is the Optimal Diet for the Prevention of Atherosclerotic Cardiovascular Disease? — The Skeptical Cardiologist

The skeptical cardiologist was asked to give a lecture in July on diet to the cardiology fellows in our training program at Saint Louis University. Needless to say, I didn’t hew to current recommendations from the American Heart Association or the Dietary Guidelines for Americans. For example, these recommendations are still promoting the narrative that…

What is the Optimal Diet for the Prevention of Atherosclerotic Cardiovascular Disease? — The Skeptical Cardiologist

Great lecture. Thank you Dr. Pearson.

Quote for Today – 10.29.22

Yes, change is the basic law of nature. But the changes wrought by the passage of time affects individuals and institutions in different ways. According to Darwin’s Origin of Species, it is not the most intellectual of the species that survives; it is not the strongest that survives; but the species that survives is the one that is able best to adapt and adjust to the changing environment in which it finds itself. Applying this theoretical concept to us as individuals, we can state that the civilization that is able to survive is the one that is able to adapt to the changing physical, social, political, moral, and spiritual environment in which it finds itself.

From a speech delivered in 1963 by a Louisiana State University business professor Leon C. Megginson at the convention of the Southwestern Social Science Association. The text of his address was published in the quarterly journal of the association. — https://quoteinvestigator.com/2014/05/04/adapt/

The quote above cites Darwin as the source of the phrase in bold.

Darwin never said it. https://www.darwinproject.ac.uk/people/about-darwin/six-things-darwin-never-said

Aging Well

Previous studies on aging have found that how people thought about themselves at age 50 predicted a wide range of future health outcomes up to 40 years later — cardiovascular events, memory, balance, will to live, hospitalizations; even mortality.”Previous research has shown that people who have positive views of aging at 50 live 7.5 years longer, on average, than people who don’t,” said Karen Hooker, co-author of the study and the Jo Anne Leonard Petersen Endowed Chair in Gerontology and Family Studies at OSU.

Oregon State University. “‘Aging well’ greatly affected by hopes and fears for later life.” ScienceDaily. http://www.sciencedaily.com/releases/2021/01/210121150929.htm (accessed January 23, 2021).

Journal Reference – Shelbie G. Turner, Karen Hooker. Are Thoughts About the Future Associated With Perceptions in the Present?: Optimism, Possible Selves, and Self-Perceptions of Aging. The International Journal of Aging and Human Development, 2020; 009141502098188 DOI: 10.1177/0091415020981883

Quote for Today – 09.22.22

Charlie Munger, the billionaire partner to Warren Buffett at Berkshire Hathaway, describes his friend’s day as 80 percent reading—often five hundred pages. Before he invests his client’s money in a company, Buffett puts the odds in his favor by reading everything he possibly can about the company itself and the broader industry. He is not always right, but he is always informed. We might imagine him flying around on private jets, wheeling and dealing, when in fact he is more likely sitting at his desk, reading everything from the great books to technical analysis.

Mr. Buffett’s reading habit provides a powerful lesson for all of us. But most Americans read almost nothing. A friend who teaches at a large public university thinks less than half of his incoming freshmen have ever read a single book in full.

Jeff Deist President of the Mises Institute. Five Keys to Professional and Personal Development accessed online 9/22/22 — https://mises.org/wire/five-keys-professional-and-personal-development

Some good advice, no matter what stage in life you find yourself. This talk was delivered on September 2, 2022, to a student workshop at the Ron Paul Institute conference in northern Virginia.

  1. Sift
  2. Read
  3. Learn Continuously
  4. Avoid Arguments
  5. Promote People, Not Just Ideas

Another Sweet Saturday – 09.17.22

Our 1-year RCT indicated that a lifestyle intervention program can be highly successful in older adults with diabetes and chronic comorbidities. In this specific population, lifestyle intervention not only improved glycemic control associated with improved insulin action and secretion but also improved age-relevant outcomes such as body composition, physical function, and quality of life.

Alessandra Celli, Yoann Barnouin, Bryan Jiang, Dean Blevins, Georgia Colleluori, Sanjay Mediwala, Reina Armamento-Villareal, Clifford Qualls, Dennis T. Villareal; Lifestyle Intervention Strategy to Treat Diabetes in Older Adults: A Randomized Controlled Trial. Diabetes Care 1 September 2022; 45 (9): 1943–1952. https://doi.org/10.2337/dc22-0338

From the periods 1988–1994 to 2017 to March 2020, there was an increase in the prevalence of diagnosed diabetes (from 4.6% to 11.7%), but no change in prevalence of persistent undiagnosed diabetes (from 2.23% to 2.53%) or confirmed undiagnosed diabetes (from 1.10% to 1.23%). Consequently, the proportion of all undiagnosed diabetes cases declined from 32.8% to 17.8% (persistent undiagnosed diabetes) and from 19.3% to 9.5% (confirmed undiagnosed diabetes). Undiagnosed diabetes was more prevalent in older and obese adults, racial/ethnic minorities, and those without health care access. Among persons with diabetes, Asian Americans and those without health care access had the highest proportion of undiagnosed cases, with rates ranging from 23% to 61%.

Michael Fang, Dan Wang, Josef Coresh, Elizabeth Selvin; Undiagnosed Diabetes in U.S. Adults: Prevalence and Trends. Diabetes Care 1 September 2022; 45 (9): 1994–2002. https://doi.org/10.2337/dc22-0242

Remember, Stay as Thin as You Can as Long as You Can.

Covid and…Neti Pot?

They knew that the more virus that was present in your body, the worse the impact, Baxter says. “One of our thoughts was: If we can rinse out some of the virus within 24 hours of them testing positive, then maybe we can lower the severity of that whole trajectory,” she says, including reducing the likelihood the virus could get into the lungs, where it was doing permanent, often lethal damage to many.

Medical College of Georgia at Augusta University. “Twice-daily nasal irrigation reduces COVID-related illness, death, study finds.” ScienceDaily. http://www.sciencedaily.com/releases/2022/09/220913110403.htm (accessed September 13, 2022).

Small study n=79 but still…

An Algorithm Put This Article in My News Feed

Photo by Egor Kamelev on Pexels.com

In a survival situation, you probably wouldn’t make it on bugs alone, despite what some sites would have you believe. But insects could certainly be an important part of what keeps you alive. Bugs are highly nutritious, with lots of proteins and vitamins and modest amounts of fat. Here are the things you should know.

9 Bugs to Eat in a Survival Situation (And 4 You Want to Avoid) — https://www.fieldandstream.com/story/survival/insects-to-eat-in-survival-situation/

Faithful followers know I have two blogs, this one and http://garyskitchen.net. The latter is more or less devoted to food. I debated whether to post this article link here or there. I decided here because my professional life is devoted to understanding what kills people. Obviously getting lost while hiking and running out of food can lead to an early expiration date.

The article was fun to read. You’ll enjoy it too unless you’re a conspiracy theorist.

Insect consumption has been highlighted by the UN’s Food and Agriculture Organization as an important tool in addressing food insecurity for a growing global population. And since agriculture is the second-largest greenhouse gas emitter after the energy sector, insect eating presents a compelling climate solution, too – crickets, for example, can provide the same amount of protein as cows for less than 0.1% of the emissions.

Meaty, cheesy, coconutty: a chef’s quest to prove insects taste delicious — https://www.theguardian.com/environment/2022/sep/09/insects-food-menu?amp;amp;amp

Hmm…maybe I should have posted this on https://garyskitchen.net

A Plan is Not a Strategy – Update 08.03.22

A few months ago I was thinking about retirement. The funny thing about life at “retirement age” and still working is you think about retirement a lot. See Thinking About Retirement (or just another fine Saturday Morning) While catching up on news I came across several articles on unretirement. I learned the word unretire is actually in the dictionary. See https://www.merriam-webster.com/dictionary/unretire. Rather than retire then unretire I decided I needed a plan. The more I thought about coming up with a plan the more I realized I needed a strategy instead.

So now I’m working on strategy only to realize I’ve had a strategy for many years. I’ve just never taken the time to write it down. It might be time to document my strategy. But it’s been too hot to write and Too Hot to Blog.

Take Home Message: A Plan is Not a Strategy.

Update 08.03.22

For an excellent example of strategy read this piece https://www.noceilingsnba.com/p/the-art-of-presti on how Sam Presti the General Manager of the OKC Thunder epitomizes this definition of strategy.